ArticleFrontiers in behavioral neuroscience2018
Association of Fatigue and Stress With Gray Matter Volume.
Article in Frontiers in behavioral neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An Overview of Stress Analysis Based on Physiological Signals: Systematic Review of Open Datasets and Current Trends.Sensors (Basel, Switzerland) · 2025Pooled it
- Dark Chocolate Intake May Reduce Fatigue and Mediate Cognitive Function and Gray Matter Volume in Healthy Middle-Aged Adults.Behavioural neurology · 2022Trial
- Trial
- Brain condition may mediate the association between training and work engagement.Scientific reports · 2020Trial
- Examination of the impact of curiosity and fatigue on brain condition.Scientific reports · 2025Article
- The Brain That Understands Diversity: A Pilot Study Focusing on the Triple Network.Brain sciences · 2025Article
- Smartphone app for lifestyle improvement improves brain health and boosts the vitality and cognitive function of healthy middle-aged adults.Brain and behavior · 2024Article
- Brain Healthcare Quotient as a Tool for Standardized Approach in Brain Healthcare Interventions.Life (Basel, Switzerland) · 2024Article
- Regional gray matter volume correlates to physical and mental fatigue in healthy middle-aged adults.Neuroimage. Reports · 2022Article
- Effects of Obesity, Blood Pressure, and Blood Metabolic Biomarkers on Grey Matter Brain Healthcare Quotient: A Large Cohort Study of a Magnetic Resonance Imaging Brain Screening System in Japan.Journal of clinical medicine · 2022Article
- Brain conditions mediate the association between aging and happiness.Scientific reports · 2022Article
- The Personal Trait of Spiritual Growth Is Correlated With the White Matter Integrity of the Brain.Frontiers in human neuroscience · 2022Article
- Regional Gray Matter Volume Related to High Occupational Stress in Firefighters.Journal of Korean medical science · 2021Article
- Potential Socioeconomic Effects of the COVID-19 Pandemic on Neural Development, Mental Health, and K-12 Educational Achievement.Policy insights from the behavioral and brain sciences · 2021Article
- The Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 infection.Current neurology and neuroscience reports · 2021Review
- Association between Behavioral Ambidexterity and Brain Health.Brain sciences · 2020Article
- Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection.PloS one · 2020Article
- Fish Intake May Affect Brain Structure and Improve Cognitive Ability in Healthy People.Frontiers in aging neuroscience · 2020Article
- Effects of iso-α-acids, the hop-derived bitter components in beer, on the MRI-based Brain Healthcare Quotient in healthy middle-aged to older adults.Neuropsychopharmacology reports · 2019Article
- Predicting post-experiment fatigue among healthy young adults: Random forest regression analysis.Psychological test and assessment modeling · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stress is associated with a greater risk for various health problems including reduced gray matter volume (GMV) and density in a number of brain regions. Previous studies show that neuroimaging could be a means to objectively evaluate stress. However, to date, no definite neuroimaging-derived measures are available to detect stress. In this research we used the gray-matter brain healthcare quotient (GM-BHQ), an MRI-based quotient for monitoring brain health based on GMV, as an objective scale to measure the association of stress with the whole brain. We recruited 63 healthy adults to acquire structural T1-weighted images and stress levels evaluated using three representative stress scales: the Profile of Mood States (POMS), Perceived Stress Scale (PSS) and Chalder Fatigue Scale (CFS). We found that the GM-BHQ was sensitive to fatigue and the interaction between fatigue and stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.