ReviewFrontiers in neuroscience2018
Neural Mechanisms With Respect to Different Paradigms and Relevant Regulatory Factors in Empathy for Pain.
Review in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Brain Activation Features in Response to the Expectation of Receiving Rewards Through Aggression.Brain sciences · 2025Article
- Gray matter morphology and pain-related disability in young adults with low back pain.NeuroImage · 2025Article
- Vicarious facilitation of facial responses to pain: Does the others' expression need to be painful?European journal of pain (London, England) · 2025Article
- Individual differences in vicarious pain as a shift in the self-other boundary.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Research progress on the mechanisms of pain empathy.Ibrain · 2025Review
- Exploring potential neuroimaging biomarkers for the response to non-steroidal anti-inflammatory drugs in episodic migraine.The journal of headache and pain · 2024Article
- Can the neural representation of physical pain predict empathy for pain in others?Social cognitive and affective neuroscience · 2024Article
- Psycho-Neuroendocrinology in the Rehabilitation Field: Focus on the Complex Interplay between Stress and Pain.Medicina (Kaunas, Lithuania) · 2024Review
- The Empathy for Pain Stimuli System (EPSS): Development and preliminary validation.Behavior research methods · 2024Article
- Pathophysiology of Pain and Mechanisms of Neuromodulation: A Narrative Review (A Neuron Project).Journal of pain research · 2024Review
- The vocal side of empathy: neural correlates of pain perception in spoken complaints.Social cognitive and affective neuroscience · 2023Article
- Words hurt: common and distinct neural substrates underlying nociceptive and semantic pain.Frontiers in neuroscience · 2023Article
- An Empathic Pain-Regulated Neural Circuit.Neuroscience bulletin · 2022Article
- Do Psychological Factors Influence the Elastic Properties of Soft Tissue in Subjects with Fibromyalgia? A Cross-Sectional Observational Study.Biomedicines · 2022Article
- Postural correlates of painful stimuli exposure: impact of mental simulation processes and pain-level of the stimuli.Experimental brain research · 2021Article
- Itch Matrixes.Frontiers in medicine · 2021Article
- Skin Color and Attractiveness Modulate Empathy for Pain: An Event-Related Potential Study.Frontiers in psychology · 2021Article
- Placebo Analgesia Does Not Reduce Empathy for Naturalistic Depictions of Others' Pain in a Somatosensory Specific Way.Cerebral cortex communications · 2021Article
- Influence of acute pain on valence rating of words.PloS one · 2021Observational
- Identification of the cerebral effects of paracetamol in healthy subjects: an fMRI study.British journal of pain · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Empathy for pain is thought to activate the affective-motivational components of the pain matrix, which includes the anterior insula and middle and anterior cingulate cortices, as indicated by functional magnetic resonance imaging and other methodologies. Activity in this core neural network reflects the affective experience that activates our responses to pain and lays the neural foundation for our understanding of our own emotions and those of others. Furthermore, although picture-based paradigms can activate somatosensory components of directly experienced pain, cue-based paradigms cannot. In addition to this difference, the two paradigms evoke other distinct neuronal responses. Although the automatic "perception-action" model has long been the dominant theory for pain empathy, a "bottom-up, top-down" mechanism seems to be more comprehensive and persuasive. Indeed, a variety of factors can regulate the intensity of empathy for pain through "top-down" processes. In this paper, we integrate and generalize knowledge regarding pain empathy and introduce the findings from recent studies. We also present ideas for future research into the neural mechanisms underlying pain empathy.
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