Evidence map›Paper›PMID 30087561›Full record

ArticleInternational journal of nanomedicine2018

Tailor-made PEG-DA-CuS nanoparticles enriched in tumor with the aid of retro Diels-Alder reaction triggered by their intrinsic photothermal property.

Jie Sheng, Beibei Ma, Qian Yang, Chao Zhang, Zhongying Jiang, Entomack Borrathybay

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jie ShengCollege of Electronic and Information Engineering, Yili Normal University, Micro-nano Electric Sensing Technology and Bionic Devices Key Laboratory, Yining 835000, China, jiangzhying@163.com.
Beibei MaCollege of Electronic and Information Engineering, Yili Normal University, Micro-nano Electric Sensing Technology and Bionic Devices Key Laboratory, Yining 835000, China, jiangzhying@163.com.
Qian YangCollege of Electronic and Information Engineering, Yili Normal University, Micro-nano Electric Sensing Technology and Bionic Devices Key Laboratory, Yining 835000, China, jiangzhying@163.com.
Chao ZhangPhysics School of Nanjing University, Laboratory of Solid State Microstructures, Nanjing 210093, China, jiangzhying@163.com.
Zhongying JiangCollege of Electronic and Information Engineering, Yili Normal University, Micro-nano Electric Sensing Technology and Bionic Devices Key Laboratory, Yining 835000, China, jiangzhying@163.com.
Entomack BorrathybayCollege of Biology and Geography Sciences, Yili Normal University, Yining 835000, Xinjiang, China, 1632984092@qq.com.
Yili Normal University · CNCollaborative Innovation Center of Advanced Microstructures · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn recent years, near-infrared laser-induced photothermal therapy is being considered as a promising approach to kill tumors owing to its noninvasive nature and excellent antitumor efficiency. However, the lack of ideal photothermal agents hinders further development of this technology. MATERIALS AND

methodsAiming at solving this long-standing obstacle, we report here about the polyethylene glycol (PEG)-DA modified copper sulfide (CuS) nanoparticles (NPs) (PEG-DA-CuS NPs), a kind of semiconductor photothermal agents that show excellent photothermal stability and high heat conversion efficiency. RESULTS AND DISCUSSION: Owing to the surrounding PEG, the water solubility of CuS NPs was significantly improved when circulating in blood in the body. When the NPs reached the tumors and were irradiated by a 1,064 nm laser (1 W/cm

conclusionTherefore, we believe PEG-DA-CuS NPs are able to serve as a kind of cytotoxic and efficient photothermal agent to kill cancer.

Indexed as

Cycloaddition ReactionLightTemperatureAnimalsAntineoplastic AgentsCell DeathCell ProliferationCopperHeLa CellsHumansHuman Umbilical Vein Endothelial CellsMiceNanoparticlesNeoplasmsPolyethylene GlycolsTissue DistributionAntineoplastic AgentsCoppercupric sulfidepoly(ethylene glycol)diacrylatePolyethylene Glycolsaggregation in tumorCuSexcellent photothermal stabilityhigh heat conversion efficiencyPEGretro Diels—Alder reaction

Identifiers

PMID30087561
PMCPMC6061216
OpenAlexW2884413145

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.