Evidence map›Paper›PMID 30087173›Full record

ArticlemBio2018

Identification of Two Regulators of Virulence That Are Conserved in

Michelle Palacios, Taryn A Miner, Daniel R Frederick, Victoria E Sepulveda, Joshua D Quinn, Kimberly A Walker, Virginia L Miller

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 115 citations in OpenAlex.

  1. Article
  2. Hypermucoviscosity inJournal of bacteriology · 2026
    Review
  3. TARGETING THE CAPSULE OFbioRxiv : the preprint server for biology · 2026
    Article
  4. HypervirulentMicrobiology spectrum · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The acquisition ofmBio · 2026
    Article
  15. Necrotizing Soft Tissue Infection Caused byInfection and drug resistance · 2026
    Article
  16. Antibiotic Resistance inAntibiotics (Basel, Switzerland) · 2026
    Review
  17. Epidemiological and Genomic Characteristics ofTransboundary and emerging diseases · 2026
    Article
  18. Overcoming phagocytosis resistance of hypervirulentMicrobial cell (Graz, Austria) · 2026
    Article
  19. Targeting the capsule ofFrontiers in immunology · 2026
    Article
  20. Review

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Michelle PalaciosDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA.
Taryn A MinerDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA.
Daniel R FrederickDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA.
Victoria E SepulvedaDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA.
Joshua D QuinnDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA.
Kimberly A WalkerDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA.
Virginia L MillerDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA vlmiller@med.unc.edu.
University of North Carolina at Chapel Hill · US

Funding

PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT S. SANDLER · 1985 to 2026
$30.5M
UNC Initiative for Maximizing Student DevelopmentR25GM055336 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COOK, JEANETTE GOWEN, KASH, THOMAS L. · 1996 to 2023
$12.1M
Regulators of Klebsiella VirulenceR21AI132925 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MILLER, VIRGINIA L · 2018 to 2019
$428k
Howard Hughes Medical InstituteNIAID NIH HHS R21 AI132925NIDDK NIH HHS P30 DK034987NIGMS NIH HHS R25 GM055336
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, BacterialAnimalsBacterial CapsulesBacterial ProteinsFemaleImmunity, InnateKlebsiella pneumoniaeMiceMice, Inbred C57BLMutationPhenotypePneumoniaTranscription FactorsVirulenceVirulence FactorsBacterial ProteinsTranscription FactorsVirulence FactorscapsuleEmrRhypermucoviscosityKvrAKvrBMarRSlyAST258

Identifiers

PMID30087173
PMCPMC6083908
OpenAlexW2887376036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.