Evidence map›Paper›PMID 30087163›Full record

ArticleThe Journal of experimental medicine2018

Transcription factor Etv6 regulates functional differentiation of cross-presenting classical dendritic cells.

Colleen M Lau, Ioanna Tiniakou, Oriana A Perez, Margaret E Kirkling, George S Yap, Hanno Hock, Boris Reizis

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of experimental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
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  9. Article
  10. Review
  11. Review
  12. A lncRNA identifieseLife · 2023
    Article
  13. In Vitro Generation of Murine CD8αMethods in molecular biology (Clifton, N.J.) · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Colleen M LauDepartment of Pathology, New York University School of Medicine, New York, NY.
Ioanna TiniakouDepartment of Pathology, New York University School of Medicine, New York, NY.
Oriana A PerezDepartment of Pathology, New York University School of Medicine, New York, NY.
Margaret E KirklingDepartment of Pathology, New York University School of Medicine, New York, NY.
George S YapDepartment of Medicine, Rutgers New Jersey Medical School, Newark, NJ.
Hanno HockMassachusetts General Hospital, Harvard Medical School, Boston, MA.
Boris ReizisDepartment of Pathology, New York University School of Medicine, New York, NY boris.reizis@nyumc.org.ORCID 0000-0003-1140-7853
New York University · USColumbia University Irving Medical Center · USHarvard University · USRutgers, The State University of New Jersey · US

Funding

PREDOCTORAL TRAINING GRANT IN HUMAN GENETICS &DEVELOPMET32GM007088 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI SHEN, MICHAEL M. · 1985 to 2020
$7.1M
Molecular Control of Plasmacytoid Dendritic Cell Development and FunctionR37AI072571 · NIAID · UNIVERSITY OF CHICAGO · PI Boris Reizis · 2018 to 2026
$5.3M
Training Program in Immunology and Inflammation.T32AI100853 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Susan Ruth Schwab · 2012 to 2026
$4.5M
Molecular Control of Plasmacytoid Dendritic Cell Development and FunctionR01AI072571 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REIZIS, BORIS · 2008 to 2017
$4.1M
Induction of effector lymphocyte lethargy by helminth coinfectionR01AI134040 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI GAUSE, WILLIAM CLARK, YAP, GEORGE S. · 2017 to 2021
$2.9M
Dissecting the aging of hematopoietic stem cells by genetic tracing in vivoR01AG049074 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REIZIS, BORIS · 2015 to 2019
$1.7M
Analyzing dendritic cell development by inducible lineage tracingR21AI115382 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REIZIS, BORIS · 2015 to 2016
$466k
Epigenetic Regulation of Dendritic Cell DevelopmentF31AI124661 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KIRKLING, MARGARET E · 2016 to 2018
$132k
NIAID NIH HHS F31 AI124661NIAID NIH HHS R01 AI072571NIAID NIH HHS R01 AI134040NIAID NIH HHS R21 AI115382NIAID NIH HHS R37 AI072571NIAID NIH HHS T32 AI100853NIA NIH HHS R01 AG049074NIGMS NIH HHS T32 GM007088
6 · The paper itself

Abstract

An IRF8-dependent subset of conventional dendritic cells (cDCs), termed cDC1, effectively cross-primes CD8

Indexed as

Immunity, CellularAnimalsAntigens, NeoplasmCD8 AntigensCD8-Positive T-LymphocytesDendritic CellsETS Translocation Variant 6 ProteinGene DeletionGene Expression RegulationHematopoietic Stem CellsMiceMice, KnockoutNeoplasmsProto-Oncogene Protein c-ets-1Proto-Oncogene Proteins c-etsRepressor ProteinsAntigens, NeoplasmCD8 antigen, alpha chainCD8 AntigensEts1 protein, mouseETS Translocation Variant 6 ProteinProto-Oncogene Protein c-ets-1Proto-Oncogene Proteins c-etsRepressor Proteins

Identifiers

PMID30087163
PMCPMC6122974
OpenAlexW2887830709

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.