Evidence map›Paper›PMID 30087107›Full record

ArticleBlood advances2018

CXCR5 and ICOS expression identifies a CD8 T-cell subset with T

Kieu-Suong Le, Patricia Amé-Thomas, Karin Tarte, Françoise Gondois-Rey, Samuel Granjeaud, Florence Orlanducci, Etienne D Foucher, Florence Broussais, Reda Bouabdallah, Thierry Fest and 5 more

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 37 citations in OpenAlex.

  1. C-X-C chemokine receptor type 5World journal of gastroenterology · 2025
    Trial
  2. Article
  3. Article
  4. The role of CD40L-expressing CXCR5Immunologic research · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Altered levels of circulating CD8Clinical rheumatology · 2022
    Article
  12. Antibody-suppressor CXCR5American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Kieu-Suong LeCentre de Recherche en Cancérologie de Marseille, Centre National de la Recherche Scientifique U7258/INSERM U1068, Marseille, France.
Patricia Amé-ThomasLabEx IGO, Equipe Labellisée Ligue Contre le Cancer, Etablissement Français du Sang Bretagne, Université de Rennes 1, Unité Mixte de Recherche U1236, INSERM, Rennes, France.
Karin TarteLabEx IGO, Equipe Labellisée Ligue Contre le Cancer, Etablissement Français du Sang Bretagne, Université de Rennes 1, Unité Mixte de Recherche U1236, INSERM, Rennes, France.
Françoise Gondois-ReyCentre de Recherche en Cancérologie de Marseille, Centre National de la Recherche Scientifique U7258/INSERM U1068, Marseille, France.
Samuel GranjeaudCentre de Recherche en Cancérologie de Marseille, Centre National de la Recherche Scientifique U7258/INSERM U1068, Marseille, France.
Florence OrlanducciInstitut Paoli-Calmettes, Marseille, France.
Etienne D FoucherCentre de Recherche en Cancérologie de Marseille, Centre National de la Recherche Scientifique U7258/INSERM U1068, Marseille, France.
Florence BroussaisInstitut Paoli-Calmettes, Marseille, France.
Reda BouabdallahInstitut Paoli-Calmettes, Marseille, France.
Thierry FestLabEx IGO, Equipe Labellisée Ligue Contre le Cancer, Etablissement Français du Sang Bretagne, Université de Rennes 1, Unité Mixte de Recherche U1236, INSERM, Rennes, France.
Dominique LerouxInstitut Albert Bonniot, Grenoble, France; and.
Sapna YadavilliImmuno-Oncology and Combination Discovery Performance Unit, Oncology Research and Development, GlaxoSmithKline, Collegeville, PA.
Patrick A MayesImmuno-Oncology and Combination Discovery Performance Unit, Oncology Research and Development, GlaxoSmithKline, Collegeville, PA.
Luc XerriCentre de Recherche en Cancérologie de Marseille, Centre National de la Recherche Scientifique U7258/INSERM U1068, Marseille, France.
Daniel OliveCentre de Recherche en Cancérologie de Marseille, Centre National de la Recherche Scientifique U7258/INSERM U1068, Marseille, France.
Inserm · FRInstitut Pprime · FRGlaxoSmithKline (United States) · USInstitut pour l'avancée des biosciences · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A better characterization of T-cell subsets in the microenvironment of classical Hodgkin lymphoma (cHL) would help to develop immunotherapies. Using multicolor flow cytometry, we identified in 6 of 43 cHL tissue samples a previously unrecognized subset of CD8 T cells coexpressing CXCR5 and inducible T-cell costimulator (ICOS) molecules (CD8

Indexed as

Gene Expression Regulation, NeoplasticCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell DifferentiationCytokinesFemaleHodgkin DiseaseHumansInducible T-Cell Co-Stimulator ProteinMaleNeoplasm ProteinsReceptors, CXCR5CXCR5 protein, humanCytokinesICOS protein, humanInducible T-Cell Co-Stimulator ProteinNeoplasm ProteinsReceptors, CXCR5

Identifiers

PMID30087107
PMCPMC6093730
OpenAlexW2891666280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.