Evidence map›Paper›PMID 30086767›Full record

ArticleRadiation oncology (London, England)2018

PRIMO Monte Carlo software benchmarked against a reference dosimetry dataset for 6 MV photon beams from Varian linacs.

Marcelino Hermida-López, David Sánchez-Artuñedo, Juan Francisco Calvo-Ortega

Abstract read
In one paragraph

Article in Radiation oncology (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Using PRIMO to determine the initial beam parameters of Elekta Synergy linac for electron beam energies of 6, 9, 12, and 15 MeV.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023
    Article
  4. PRIMO Monte Carlo software as a tool for commissioning of an external beam radiotherapy treatment planning system.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023
    Article
  5. Monte Carlo simulation of linac using PRIMO.Radiation oncology (London, England) · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marcelino Hermida-LópezServei de Física i Protecció Radiològica. Hospital Universitari Vall d'Hebron, Pg. Vall d'Hebron, 119-129, Barcelona, 08035, Spain. mhermida@vhebron.net.ORCID http://orcid.org/0000-0003-1137-7375
David Sánchez-ArtuñedoServei de Física i Protecció Radiològica. Hospital Universitari Vall d'Hebron, Pg. Vall d'Hebron, 119-129, Barcelona, 08035, Spain.
Juan Francisco Calvo-OrtegaServicio de Oncología Radioterápica, Hospital Quirónsalud Barcelona, Pza. Alfonso Comín, 5, Barcelona, 08023, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe software PRIMO for the Monte Carlo simulation of radiotherapy linacs could potentially act as a independent calculation system to verify the calculations of treatment planning systems. We investigated the suitability of the PRIMO default beam parameters to produce accurate dosimetric results for 6 MV photon beams from Varian Clinac 2100 linacs and 6 MV flattening-filter-free photon beams from Varian TrueBeam linacs.

methodsSimulation results with the DPM algorithm were benchmarked against a published reference dosimetry dataset based on point measurements of 25 dosimetric parameters on a large series of linacs. Studied parameters (for several field sizes and depths) were: PDD, off-axis ratios, and output factors for open fields and IMRT/SBRT-style fields. For the latter, the output factors were also determined with radiochromic film and with a small-sized ionization chamber. Benchmark data, PRIMO simulation results and our experimental results were compared.

resultsPDD, off-axis ratios, and open-field output factors obtained from the simulations with the PRIMO default beam parameters agreed with the benchmark data within 2.4% for Clinac 2100, and within 1.3% for TrueBeam. Higher differences were found for IMRT/SBRT-style output factors: up to 2.8% for Clinac 2100, and up to 3.3% for TrueBeam. Experimental output factors agreed with benchmark data within 1.0% (ionization chamber) and within 1.9% (radiochromic film).

conclusionsPRIMO default initial beam parameters for 6 MV photon beams from Varian Clinac 2100 linacs and 6 MV FFF photon beams from Varian TrueBeam linacs allowed agreement within 3.3% with a dosimetry database based on measurements of a high number of linacs. This finding represents a first step in the validation of PRIMO for the independent verification of radiotherapy plans.

Indexed as

SoftwareAlgorithmsBenchmarkingDatabases as TopicMonte Carlo MethodParticle AcceleratorsPhantoms, ImagingPhotonsRadiometryRadiotherapy DosageRadiotherapy Planning, Computer-AssistedReference StandardsUncertaintyDosimetryLinacMonte Carlo simulationPRIMO

Identifiers

PMID30086767
PMCPMC6081807

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.