Evidence map›Paper›PMID 30086475›Full record

ArticleInternational journal of surgery case reports2018

Suture granulomas developing after the treatment of oral squamous cell carcinoma.

Yukio Yoshioka, Hirotaka Nakatao, Tomoaki Hamana, Atsuko Hamada, Taku Kanda, Koichi Koizumi, Shigeaki Toratani, Tetsuji Okamoto

Open access · goldAbstract read
In one paragraph

Article in International journal of surgery case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Non-healing wounds: Can it take different diagnosis?International wound journal · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yukio YoshiokaDepartment of Molecular Oral Medicine and Maxillofacial Surgery, Division of Applied Life Science, Graduate Institute of Biomedical and Health Science, Hiroshima University, 734-8553, 1-2-3, Kasumi, Minami-ku, Hiroshima-shi, Hiroshima, Japan. Electronic address: yyosioka@hiroshima-u.ac.jp.
Hirotaka NakataoOral and Maxillofacial surgery, Hiroshima University Hospital, 734-8553, 1-2-3, Kasumi, Minami-ku, Hiroshima-shi, Hiroshima, Japan. Electronic address: nakatao@hiroshima-u.ac.jp.
Tomoaki HamanaDepartment of Molecular Oral Medicine and Maxillofacial Surgery, Division of Applied Life Science, Graduate Institute of Biomedical and Health Science, Hiroshima University, 734-8553, 1-2-3, Kasumi, Minami-ku, Hiroshima-shi, Hiroshima, Japan. Electronic address: tomoh57@hiroshima-u.ac.jp.
Atsuko HamadaOral and Maxillofacial surgery, Hiroshima University Hospital, 734-8553, 1-2-3, Kasumi, Minami-ku, Hiroshima-shi, Hiroshima, Japan. Electronic address: hamaco@hiroshima-u.ac.jp.
Taku KandaOral and Maxillofacial surgery, Hiroshima University Hospital, 734-8553, 1-2-3, Kasumi, Minami-ku, Hiroshima-shi, Hiroshima, Japan. Electronic address: kanataku@hiroshima-u.ac.jp.
Koichi KoizumiDepartment of Molecular Oral Medicine and Maxillofacial Surgery, Division of Applied Life Science, Graduate Institute of Biomedical and Health Science, Hiroshima University, 734-8553, 1-2-3, Kasumi, Minami-ku, Hiroshima-shi, Hiroshima, Japan. Electronic address: kkoizumi@hiroshima-u.ac.jp.
Shigeaki TorataniDepartment of Molecular Oral Medicine and Maxillofacial Surgery, Division of Applied Life Science, Graduate Institute of Biomedical and Health Science, Hiroshima University, 734-8553, 1-2-3, Kasumi, Minami-ku, Hiroshima-shi, Hiroshima, Japan. Electronic address: tora@hiroshima-u.ac.jp.
Tetsuji OkamotoDepartment of Molecular Oral Medicine and Maxillofacial Surgery, Division of Applied Life Science, Graduate Institute of Biomedical and Health Science, Hiroshima University, 734-8553, 1-2-3, Kasumi, Minami-ku, Hiroshima-shi, Hiroshima, Japan. Electronic address: tetsuok@hiroshima-u.ac.jp.
Hiroshima University · JPHiroshima University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSuture granuloma is a benign tumor that develops because of the presence of surgical suture materials. It commonly occurs several years after different types of surgeries. Here we report a case involving a 64-year-old man who underwent head and neck surgery for oral squamous cell carcinoma and developed multiple suture granulomas mimicking tumor recurrence in the radiation field just a few days after the completion of adjuvant chemoradiation therapy. PRESENTATION OF CASE: The patient underwent surgery for lymph node metastasis in the neck at 6 months after the resection of primary oral squamous cell carcinoma. Fifteen days after the completion of adjuvant chemoradiation therapy at a total dose of 50 Gy, small nodules appeared in the radiation field, along the areas of the subcutaneous surgical sutures. Cancer recurrence was initially suspected, but histopathological analysis of a biopsy specimen confirmed foreign body granuloma. DISCUSSION: Chemoradiation therapy may enhance the immunoreaction of macrophages in the radiation field and promote the formation of granulation tissue in a short period of time. In addition, cisplatin, which was concurrently administered with radiation in our case, could have influenced the development of the suture granuloma.

conclusionIn addition to tumor recurrence, suture granulomas should be considered a differential diagnosis for nodules occurring after surgery, even if they develop in the field of radiation.

Indexed as

Absorbable suturesChemoradiationForeign body granulomaNeck dissectionOral squamous cell carcinomaSuture granuloma

Identifiers

PMID30086475
PMCPMC6085222
OpenAlexW2884270095

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.