Evidence map›Paper›PMID 30086142›Full record

ArticlePloS one2018

Deficits in nominal reference identify thought disordered speech in a narrative production task.

Gabriel Sevilla, Joana Rosselló, Raymond Salvador, Salvador Sarró, Laura López-Araquistain, Edith Pomarol-Clotet, Wolfram Hinzen

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Gabriel SevillaGrammar & Cognition Lab, Department of Translation and Language Sciences, Universitat Pompeu Fabra, Barcelona, Spain.ORCID 0000-0002-7446-2983
Joana RossellóGrammar & Cognition Lab, Department of Catalan Philology and General Linguistics, Universitat de Barcelona, Barcelona, Spain.
Raymond SalvadorFIDMAG Germanes Hospitalàries Research Foundation, Barcelona, Spain.
Salvador SarróFIDMAG Germanes Hospitalàries Research Foundation, Barcelona, Spain.ORCID 0000-0003-1835-2189
Laura López-AraquistainBenito Menni Complex Assistencial en Salut Mental, Sant Boi de Llobregat, Barcelona, Spain.
Edith Pomarol-ClotetFIDMAG Germanes Hospitalàries Research Foundation, Barcelona, Spain.
Wolfram HinzenGrammar & Cognition Lab, Department of Translation and Language Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Centro de Investigación Biomédica en Red de Salud Mental · ESInstitució Catalana de Recerca i Estudis Avançats · ESUniversitat de Barcelona · ESUniversitat Pompeu Fabra · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Formal thought disorder (TD) is a neuropathology manifest in formal language dysfunction, but few behavioural linguistic studies exist. These have highlighted problems in the domain of semantics and more specifically of reference. Here we aimed for a more complete and systematic linguistic model of TD, focused on (i) a more in-depth analysis of anomalies of reference as depending on the grammatical construction type in which they occur, and (ii) measures of formal grammatical complexity and errors. Narrative speech obtained from 40 patients with schizophrenia, 20 with TD and 20 without, and from 14 healthy controls matched on pre-morbid IQ, was rated blindly. Results showed that of 10 linguistic variables annotated, 4 showed significant differences between groups, including the two patient groups. These all concerned mis-uses of noun phrases (NPs) for purposes of reference, but showed sensitivity to how NPs were classed: definite and pronominal forms of reference were more affected than indefinite and non-pronominal (lexical) NPs. None of the measures of formal grammatical complexity and errors distinguished groups. We conclude that TD exhibits a specific and differentiated linguistic profile, which can illuminate TD neuro-cognitively and inform future neuroimaging studies, and can have clinical utility as a linguistic biomarker.

Indexed as

AdultCognition DisordersFemaleHumansMaleMiddle AgedNarrationNeuropsychological TestsSchizophreniaSchizophrenic LanguageSpeech DisordersThinking

Identifiers

PMID30086142
PMCPMC6080774
OpenAlexW2885985215

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.