Evidence map›Paper›PMID 30086137›Full record

ArticlePloS one2018

Macro-morphological characterization and kinetics of Mortierella alpina colonies during batch cultivation.

Xue Fang, Genhai Zhao, Jun Dai, Hui Liu, Peng Wang, Li Wang, Junying Song, Zhiming Zheng

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Optimization of the Fermentative Production ofBioengineering (Basel, Switzerland) · 2022
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xue FangKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Insitutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, China.
Genhai ZhaoKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Insitutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, China.ORCID 0000-0001-6343-6053
Jun DaiKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Insitutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, China.
Hui LiuKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Insitutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, China.
Peng WangKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Insitutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, China.
Li WangKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Insitutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, China.
Junying SongKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Insitutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, China.
Zhiming ZhengKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Insitutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An effective method for research of macro-morphological characterization and its kinetics was developed by studying the macro-morphological characteristics of Mortierella alpina, an oleaginous zygomycete widely used to produce lipids rich in PUFA, in function of culture medium composition and to link morphological features of fungus with the level of lipid production. A number of distinct morphological forms including hollow pellets, fluffy pellets and freely dispersed mycelia were obtained by changing the fermentation factors. By fitting a Logistic curve, the maximum specific growth rate (μmax)was obtained, which determined the final mycelia morphology. μmax of 0.6584 in three kind of morphological forms is the more appropriate. According to the Luedeking-Piret equation fitting, α≠0 and β≠0, lipid production was partially associated with the hyphal growth, fluffy pellets which turn glucose into lipidwas more effective than the other two kinds of morphological forms.

Indexed as

Batch Cell Culture TechniquesCulture MediaFermentationKineticsLipid MetabolismMortierellaMyceliumCulture Media

Identifiers

PMID30086137
PMCPMC6080745

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.