ArticleTransplantation2019
Patient Functional Status at Transplant and Its Impact on Posttransplant Survival of Adult Deceased-donor Kidney Recipients.
Article in Transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Using Information Available at the Time of Donor Offer to Predict Kidney Transplant Survival Outcomes: A Systematic Review of Prediction Models.Transplant international : official journal of the European Society for Organ Transplantation · 2022Pooled it
- Infections after kidney transplantation. Does age matter?Clinical transplantation · 2019Trial
- Center Differences in PreTransplant Functional Status and Its Association With Survival After Heart Transplantation.Clinical transplantation · 2026Article
- A Prediction Model for Risk of Death in Kidney Transplant Recipients.JAMA network open · 2026Article
- Risk Factors and Outcomes of Reintubation Following Combined Heart-Lung Transplantation.Clinical transplantation · 2026Article
- Reduced Functional Status among Kidney Transplant Recipients over Time and Associated Risks Post-Transplant.Clinical transplantation · 2025Article
- Using Unsupervised Clustering to Characterize Phenotypes Among Older Kidney Transplant Recipients: A Cohort Study.Canadian journal of kidney health and disease · 2025Article
- Associations of Pretransplant Patient-Reported Outcomes Measurement Information System Physical Function Score With Kidney Transplant Outcomes.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Recipient functional status impacts on short and long-term intestinal transplant outcomes in United States adults.World journal of transplantation · 2024Article
- Analysis of Individual Components of Frailty in Simultaneous Pancreas and Kidney, and Solitary Pancreas Transplant Recipients.Transplantation direct · 2023Article
- Predicting a kidney transplant patient's pre-transplant functional status based on information from waitlist registration.Scientific reports · 2023Article
- Poor Physical Function Trajectory Predicts Impaired Patient Survival in Older Recipients of Deceased Donor Kidneys: A Prospective Cohort Study.Transplantation direct · 2022Article
- Distinct Phenotypes of Kidney Transplant Recipients in the United States with Limited Functional Status as Identified through Machine Learning Consensus Clustering.Journal of personalized medicine · 2022Article
- A Comorbidity Index and Pretransplant Physical Status Predict Survival in Older Kidney Transplant Recipients: A National Prospective Study.Transplantation direct · 2022Article
- Cytomegalovirus Serostatus and Functional Impairment in Liver Transplant Recipients in the Current Era.Viruses · 2021Article
- Karnofsky Performance Score-Failure to Thrive as a Frailty Proxy?Transplantation direct · 2021Article
- Impact of Functional Status on Outcomes of Simultaneous Pancreas-kidney Transplantation: Risks and Opportunities for Patient Benefit.Transplantation direct · 2020Article
- Kidney transplant outcomes in recipients with visual, hearing, physical and walking impairments: a prospective cohort study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Article
- An overview of frailty in kidney transplantation: measurement, management and future considerations.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Review
- Association of Karnofsky Performance Status with waitlist mortality among older and younger adults awaiting kidney transplantation.Clinical transplantation · 2020Article
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4 authors.
Funding
Abstract
backgroundRecorded at the time of transplant and reported to the Organ Procurement and Transplantation Network, patient's functional status is measured using the Karnofsky performance score (KPS), ranging 0 to 100. Functional status analysis may provide insights on candidate listing and posttransplant survival outcomes for deceased-donor kidney transplants.
methodsThe cohort consisted of adult deceased-donor kidney transplant recipients transplanted beginning January 2007. One-year and 3-year Cox models for posttransplant survival were fitted with current Scientific Registry of Transplant Recipients (SRTR) variables and KPS. Comparative analyses were performed between the SRTR model without KPS and augmented model with it. Using the augmented model, we examined the impact of Kidney Donor Profile Index on posttransplant survivals for 5 different KPS strata: 10 to 30, 40 to 50, 60 to 70, 80 to 90, and 100.
resultsComparative analyses showed that KPS was a statistically significant predictor for posttransplant survival: it improved model calibration, discrimination, and predictive accuracy. From the augmented model, the survival curves illustrated that recipients with KPS 40 to 50 and kidneys with Kidney Donor Profile Index as high as 99 have expected survival probabilities of above 90% in 1 year and above 80% in 3 years. The expected survival probabilities improve as KPS increases. Recipients with KPS 10 to 30 have the worst survival probability, even if they received high-quality kidneys.
conclusionsInsights from the survival analyses recommend possible inclusion of functional status into SRTR's risk-adjusted models. Moreover, they invite further examination of its use to improve current listing and transplantation strategies at transplant centers and potentially reduce deceased-donor kidney discard rate.
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