Evidence map›Paper›PMID 30085250›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2019

Clinical Manifestations and Bacterial Genomic Analysis of Group A Streptococcus Strains That Cause Pediatric Toxic Shock Syndrome.

Roman Deniskin, Brittany Shah, Flor M Muñoz, Anthony R Flores

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Frontiers in cellular and infection microbiology · 2025
    Article
  4. Review
  5. Antibiotics (Basel, Switzerland) · 2023
    Article
  6. Population Genomics ofmSystems · 2021
    Article
  7. PersistentCase reports in plastic surgery & hand surgery · 2020
    Article
  8. Group A Streptococcal Virulence: New Lessons.Journal of the Pediatric Infectious Diseases Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Roman DeniskinDepartment of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston.
Brittany ShahDivision of Infectious Diseases, Department of Pediatrics, Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Sciences Center at Houston.
Flor M MuñozDepartment of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston.
Anthony R FloresDivision of Infectious Diseases, Department of Pediatrics, Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, University of Texas Health Sciences Center at Houston.

Funding

Contribution of LiaFSR to pathogenesis and carriage of group A StreptococcusR01AI125216 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FLORES, ANTHONY RICHARD · 2017 to 2021
$1.9M
NIAID NIH HHS R01 AI125216
6 · The paper itself

Abstract

We report here 18 cases of pediatric group A streptococcal toxic shock syndrome, associated clinical findings, and bacterial molecular genetic characteristics discovered through whole-genome sequencing. This comparative whole-genome sequencing revealed unique gene content (speK) and polymorphisms (dpiB) in emm87 group A Streptococcus, the relative contributions of which, in combination with the host response, in the development of streptococcal toxic shock syndrome remain to be elucidated.

Indexed as

Antigens, BacterialBacterial Outer Membrane ProteinsChildChild, PreschoolFemaleGenes, BacterialGenotyping TechniquesHumansMalePhylogenyPolymorphism, Single NucleotideRetrospective StudiesShock, SepticStreptococcal InfectionsStreptococcus pyogenesWhole Genome SequencingAntigens, BacterialBacterial Outer Membrane Proteinsemm typegroup A StreptococcusinvasiveshockSTSS

Identifiers

PMID30085250
PMCPMC6601382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.