Evidence map›Paper›PMID 30084955›Full record

ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2018

Hantavirus Cardiopulmonary Syndrome Due to Imported Andes Hantavirus Infection in Switzerland: A Multidisciplinary Challenge, Two Cases and a Literature Review.

Andrea B Kuenzli, Jonas Marschall, Joerg C Schefold, Margaret Schafer, Oliver B Engler, Rahel Ackermann-Gäumann, David C Reineke, Franziska Suter-Riniker, Cornelia Staehelin

Open access · hybridAbstract readCase ReportsReview
In one paragraph

Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Immune Regulation in the Testis and Epididymis.Advances in experimental medicine and biology · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Effective chemical virus inactivation of patient serum compatible with accurate serodiagnosis of infections.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2019
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Andrea B KuenzliBern University Hospital and University of Bern, Switzerland.
Jonas MarschallBern University Hospital and University of Bern, Switzerland.
Joerg C SchefoldBern University Hospital and University of Bern, Switzerland.
Margaret SchaferBern University Hospital and University of Bern, Switzerland.
Oliver B EnglerSpiez Laboratory, Federal Office for Civil Protection, Switzerland.
Rahel Ackermann-GäumannSpiez Laboratory, Federal Office for Civil Protection, Switzerland.
David C ReinekeBern University Hospital and University of Bern, Switzerland.
Franziska Suter-RinikerInstitute for Infectious Diseases, University of Bern, Switzerland.
Cornelia StaehelinBern University Hospital and University of Bern, Switzerland.
University of Bern · CHSpiez Laboratory · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two travellers returning from South America were diagnosed with Andes hantavirus infection, the only member of the Hantaviridae family known to be transmitted from person to person. We describe the clinical course and therapeutic and infection control measures. While both patients showed high viral load (VL) and shedding over several months, 1 patient recovered within 1 week from severe respiratory illness that required noninvasive ventilation, whereas the second patient developed severe hantavirus cardiopulmonary syndrome that required extracorporeal membrane oxygenation for 27 days. The clinical course in the latter patient was complicated by severe disseminated intravascular coagulopathy with diffuse hemorrhage that necessitated mass transfusions, as well as by multiple organ failure, including the need for renal replacement therapy. Results of VL in blood, respiratory secretions, and semen for the first 9 months of follow-up are reported. To our knowledge, these are the first cases of Andes hantavirus infection detected in Europe.

Indexed as

Travel-Related IllnessAntibodies, ViralCommunicable Diseases, ImportedDisseminated Intravascular CoagulationFemaleHantavirus Pulmonary SyndromeHumansMaleMiddle AgedSouth AmericaSwitzerlandThoraxTomography, X-Ray ComputedViral LoadAntibodies, Viral

Identifiers

PMID30084955
PMCPMC6233683
OpenAlexW2886313076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.