Evidence map›Paper›PMID 30084904›Full record

ReviewBritish medical bulletin2018

Being a good egg in the 21st century.

Richard A Anderson, Evelyn E Telfer

Abstract readReview
In one paragraph

Review in British medical bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Apoptosis promotes fertility inbioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Human FollicleFrontiers in endocrinology · 2020
    Review
  11. Article
  12. The existence and potential of germline stem cells in the adult mammalian ovary.Climacteric : the journal of the International Menopause Society · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Richard A AndersonMRC Centre for Reproductive Health, Queen's Medical Research Institute, University of Edinburgh and Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
Evelyn E TelferMRC Centre for Reproductive Health, Queen's Medical Research Institute, University of Edinburgh and Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.

Funding

Medical Research Council G0901839Medical Research Council G1100357Medical Research Council MR/L00299X/1Medical Research Council MR/N022556/1Medical Research Council MR/R003246/1
6 · The paper itself

Abstract

Introduction: Women are increasingly having children at a later age, but this can conflict with declining fertility in the later 30's and thereafter. Areas of agreement: Declining egg quality and quantity with age are well-established, although egg quality can only be surmised from reproductive success or failure. Areas of controversy: Whether increasing the number of eggs that can be obtained from ovarian stimulation is of value, and whether there are precursor cells within the adult ovary that could become mature eggs. Growing points: There is increasing use of donated eggs by older women to enhance their chances of conception. The storage of frozen eggs for potential use later in life is also becoming more common. Areas timely for developing research: Understanding of growth initiation of follicles and development of an artificial ovary may lead to the ability to affect fertility and reproductive lifespan.

Indexed as

AdultAgingFemaleFertilityFertilizationHumansOvarian Function TestsOvary

Identifiers

PMID30084904
PMCPMC6127894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.