Evidence map›Paper›PMID 30084634›Full record

ArticleACS sensors2018

Ultrasensitive Detection of Bacterial Protein Toxins on Patterned Microarray via Surface Plasmon Resonance Imaging with Signal Amplification by Conjugate Nanoparticle Clusters.

Alexander Lambert, Zhanjun Yang, Wei Cheng, Zhenda Lu, Ying Liu, Quan Cheng

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS sensors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alexander LambertDepartment of Chemistry , University of California , Riverside , California 92521 , United States.
Zhanjun YangDepartment of Chemistry , University of California , Riverside , California 92521 , United States.
Wei ChengDepartment of Chemistry , University of California , Riverside , California 92521 , United States.
Zhenda LuCollege of Engineering and Applied Science , Nanjing University , Nanjing 210023 , China.ORCID 0000-0002-9616-8814
Ying LiuDepartment of Chemistry , Nanjing University , Nanjing 210023 , China.ORCID 0000-0001-5718-7804
Quan ChengDepartment of Chemistry , University of California , Riverside , California 92521 , United States.ORCID 0000-0003-0934-358X
University of California, Riverside · USNanjing University · CN

Funding

Research Training in Environmental ToxicologyT32ES018827 · NIEHS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Yinsheng Wang · 2010 to 2026
$5.3M
NIEHS NIH HHS T32 ES018827
6 · The paper itself

Abstract

Sensitive detection and monitoring of biological interactions in a high throughput, multiplexed array format has numerous advantages. We report here a method to enhance detection sensitivity in surface plasmon resonance (SPR) spectroscopy and SPR imaging via the effect of accumulation of conjugated nanoparticles of varying sizes. Bacterial cholera toxin (CT) was chosen for the demonstration of enhanced immunoassay by SPR. After immobilization of CT on a gold surface, specific recognition is achieved by biotinylated anti-CT. The signal is amplified by the attachment of biotinylated 20 nm AuNP via streptavidin bridge, followed by attachment of 5 nm streptavidin-functionalized Fe

Indexed as

Bacterial ProteinsBiotinCalibrationCholera ToxinGoldImmunoassayLimit of DetectionMagnetite NanoparticlesParticle SizeStreptavidinSurface Plasmon ResonanceBacterial ProteinsBiotinCholera ToxinGoldMagnetite NanoparticlesStreptavidinmicroarraynanoparticle amplificationplasmonic microchipSPR imagingsurface plasmon resonance

Identifiers

PMID30084634
PMCPMC11938696
OpenAlexW2887176256

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.