ArticleThe Journal of comparative neurology2018
Neuroarchitecture of the Drosophila central complex: A catalog of nodulus and asymmetrical body neurons and a revision of the protocerebral bridge catalog.
Article in The Journal of comparative neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A connectome and analysis of the adulteLife · 2020Pooled it
- Cellular and functional dissection of the octopaminergic and tyraminergic system in the Drosophila brain.Current biology : CB · 2026Article
- Fluorescently-labeled split-QF hemidrivers: simplifying and enhancing methods enabling intersectional targeting of discrete cell types.bioRxiv : the preprint server for biology · 2026Article
- Sequential formation ofScience advances · 2026Article
- Article
- Finding a path: local search behavior of Drosophila larvae.The Journal of experimental biology · 2025Article
- SIFa peptidergic neurons orchestrate the internal states and energy balance of male Drosophila melanogaster.PLoS biology · 2025Article
- Neuropeptide-mediated synaptic plasticity regulates context-dependent mating behaviors in Drosophila.PLoS biology · 2025Article
- Wolbachia-mediated reduction in the glutamate receptor mGluR promotes female promiscuity and bacterial spread.Cell reports · 2025Article
- Article
- Cell type-specific driver lines targeting theeLife · 2025Article
- Transcriptional complexity in the insect central complex: single nuclei RNA-sequencing of adult brain neurons derived from type 2 neuroblasts.bioRxiv : the preprint server for biology · 2025Article
- Article
- A split-GAL4 driver line resource foreLife · 2025Article
- Cell type-specific driver lines targeting thebioRxiv : the preprint server for biology · 2025Article
- Rapid lightsheet fluorescence imaging of whole Drosophila brains at nanoscale resolution by potassium acrylate-based expansion microscopy.Nature communications · 2024Article
- Castor is a temporal transcription factor that specifies early born central complex neuron identity.Development (Cambridge, England) · 2024Article
- Neuroarchitecture of the Central Complex in the Madeira Cockroach Rhyparobia maderae: Tangential Neurons.The Journal of comparative neurology · 2024Article
- A computational model for angular velocity integration in a locust heading circuit.PLoS computational biology · 2024Article
- A Brief Overview of Ethanol Tolerance and Its Potential Association with Circadian Rhythm inInternational journal of molecular sciences · 2024Review
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The central complex, a set of neuropils in the center of the insect brain, plays a crucial role in spatial aspects of sensory integration and motor control. Stereotyped neurons interconnect these neuropils with one another and with accessory structures. We screened over 5,000 Drosophila melanogaster GAL4 lines for expression in two neuropils, the noduli (NO) of the central complex and the asymmetrical body (AB), and used multicolor stochastic labeling to analyze the morphology, polarity, and organization of individual cells in a subset of the GAL4 lines that showed expression in these neuropils. We identified nine NO and three AB cell types and describe them here. The morphology of the NO neurons suggests that they receive input primarily in the lateral accessory lobe and send output to each of the six paired noduli. We demonstrate that the AB is a bilateral structure which exhibits asymmetry in size between the left and right bodies. We show that the AB neurons directly connect the AB to the central complex and accessory neuropils, that they target both the left and right ABs, and that one cell type preferentially innervates the right AB. We propose that the AB be considered a central complex neuropil in Drosophila. Finally, we present highly restricted GAL4 lines for most identified protocerebral bridge, NO, and AB cell types. These lines, generated using the split-GAL4 method, will facilitate anatomical studies, behavioral assays, and physiological experiments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.