Evidence map›Paper›PMID 30084493›Full record

ArticleClinical cardiology2018

Left ventricular thrombosis in acute anterior myocardial infarction: Evaluation of hospital mortality, thromboembolism, and bleeding.

Pradhum Ram, Mahek Shah, Natee Sirinvaravong, Kevin Bryan Lo, Shantanu Patil, Brijesh Patel, Byomesh Tripathi, Lohit Garg, Vincent Figueredo

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Pradhum RamDepartment of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania.ORCID http://orcid.org/0000-0003-3406-9260
Mahek ShahDivision of Cardiology, Lehigh Valley Hospital Network, Allentown, Pennsylvania.ORCID http://orcid.org/0000-0002-5065-3355
Natee SirinvaravongDepartment of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania.
Kevin Bryan LoDepartment of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania.ORCID http://orcid.org/0000-0001-7088-6677
Shantanu PatilDepartment of Medicine, University of Pittsburg Medical Center, Pittsburg, Pennsylvania.
Brijesh PatelDivision of Cardiology, Lehigh Valley Hospital Network, Allentown, Pennsylvania.ORCID http://orcid.org/0000-0001-8973-8228
Byomesh TripathiDepartment of Medicine, Mount Sinai St Luke's-Roosevelt Hospital, New York, New York.
Lohit GargDivision of Cardiology, Lehigh Valley Hospital Network, Allentown, Pennsylvania.
Vincent FigueredoDepartment of Cardiology, Albert Einstein Medical Center, Philadelphia, Pennsylvania.ORCID http://orcid.org/0000-0003-0301-5649
Einstein Medical Center Philadelphia · USLehigh Valley Hospital-Pocono · USPittsburg State University · USSt. Luke's-Roosevelt Hospital Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft ventricular thrombosis (LVT) is a well-known complication of acute myocardial infarction, most commonly seen in anterior wall ST-segment elevation myocardial infarction (STEMI). It is associated with systemic thromboembolism. HYPOTHESIS: Our aim was to evaluate the impact of LVT on in-hospital mortality, thromboembolism, and bleeding in patients with anterior STEMI.

methodsData was collected from the Nationwide Inpatient Sample where patients with a primary diagnosis of "Anterior STEMI" [ICD9-CM code 410.1] were included. Comparisons were made between patients with LVT [ICD9-CM code 429.79] vs those without using propensity score matching (PSM).

resultsFrom 2002 to 2014, there were 157 891 cases of anterior STEMI. Among these, 649 (0.4%) had LVT. Post-PSM, there was no difference in in-hospital mortality between the groups with LVT and without (7.3% vs 8.6%). Thromboembolic event rate was higher with LVT compared to those without LVT (7.3% vs 2.1%). There was no difference in bleeding events between patients with LVT and those without (2.9% vs 3.2%). The baseline average length of stay in the group with LVT was longer than the group without LVT (7.9 ± 6.7 days vs 5.1 ± 6.0 days). The average hospitalization-related costs were also significantly higher among patients with LVT compared to those without (95 598 USD vs 66 641 USD per stay) at baseline.

conclusionAmong patients hospitalized with anterior STEMI, presence of LVT is associated with increased thromboembolic events, average length of hospital stay and average cost of hospitalization. However, it is not associated with increased in-hospital mortality or bleeding events.

Indexed as

Anterior Wall Myocardial InfarctionEchocardiographyFemaleFibrinolytic AgentsFollow-Up StudiesHeart DiseasesHeart VentriclesHemorrhageHospital MortalityHumansIncidenceMaleMiddle AgedPercutaneous Coronary InterventionPropensity ScoreRetrospective StudiesFibrinolytic Agentsanterior STEMIcardiac thrombosisleft ventricular thrombusthromboembolism

Identifiers

PMID30084493
PMCPMC6489802
OpenAlexW2887116926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.