Evidence map›Paper›PMID 30084342›Full record

Trial reportThe American journal of tropical medicine and hygiene2018

Antigen Detection in Urine for Noninvasive Diagnosis and Treatment Monitoring of Visceral Leishmaniasis in Human Immunodeficiency Virus Coinfected Patients: An Exploratory Analysis from Ethiopia.

Florian Vogt, Bewketu Mengesha, Helen Asmamaw, Tigist Mekonnen, Helina Fikre, Yegnasew Takele, Emebet Adem, Rezika Mohammed, Koert Ritmeijer, Wim Adriaensen and 3 more

Open access · bronzeAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Blood Parasite Load as an Early Marker to Predict Treatment Response in Visceral Leishmaniasis in Eastern Africa.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Trial
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Recent advances and new strategies in Leishmaniasis diagnosis.Applied microbiology and biotechnology · 2020
    Review
  14. Article
  15. Tissue Parasites in HIV Infection.Current infectious disease reports · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Florian VogtDepartment of Clinical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium.
Bewketu MengeshaLeishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia.
Helen AsmamawGondar University Hospital, University of Gondar, Gondar, Ethiopia.
Tigist MekonnenLeishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia.
Helina FikreLeishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia.
Yegnasew TakeleLeishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia.
Emebet AdemLeishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia.
Rezika MohammedLeishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia.
Koert RitmeijerPublic Health Department, Médecins Sans Frontières, Amsterdam, The Netherlands.
Wim AdriaensenDepartment of Clinical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium.
Yayehirad MelsewDepartment of Epidemiology and Biostatistics, University of Gondar, Gondar, Ethiopia.
Johan van GriensvenDepartment of Clinical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium.
Ermias DiroLeishmaniasis Research and Treatment Center, University of Gondar, Gondar, Ethiopia.
University of Gondar · ETInstituut voor Tropische Geneeskunde · BEMédecins Sans Frontières · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis of visceral leishmaniasis (VL) and assessment of treatment response in human immunodeficiency virus (HIV)-coinfected patients still relies on invasive tissue aspiration. This hampers scale-up and decentralization of care in resource-limited settings. Noninvasive diagnostics are urgently needed. KATEX is a frequently used latex agglutination test for

Indexed as

Antiretroviral Therapy, Highly ActiveAdultAntigens, ProtozoanAntiprotozoal AgentsCD4 Lymphocyte CountCD4-Positive T-LymphocytesCoinfectionEthiopiaFemaleHIVHIV InfectionsHumansLatex Fixation TestsLeishmania donovaniLeishmaniasis, VisceralMaleAntigens, ProtozoanAntiprotozoal AgentsPentamidineReagent Kits, Diagnostic

Identifiers

PMID30084342
PMCPMC6159592
OpenAlexW2885165714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.