Evidence map›Paper›PMID 30084286›Full record

SynthesisThe Journal of international medical research2018

Efficacy of Chinese herbal medicine in treatment of allergic rhinitis in children: a meta-analysis of 19 randomized controlled trials.

Zhipan Zheng, Zhenshuang Sun, Xueping Zhou, Zhongying Zhou

Open access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in The Journal of international medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Efficacy and Safety of Guizhi Decoction AssociatedFormulas for Allergic Rhinitis: A Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  13. Traditional Chinese Medicine (TCM) and Allergic Diseases.Current allergy and asthma reports · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhipan Zheng1 First Clinical College of Nanjing University of Chinese Medicine, Nanjing, Jangsu Province, China.
Zhenshuang Sun1 First Clinical College of Nanjing University of Chinese Medicine, Nanjing, Jangsu Province, China.
Xueping Zhou2 Nanjing University of Chinese Medicine, Jangsu Province, China.
Zhongying Zhou2 Nanjing University of Chinese Medicine, Jangsu Province, China.ORCID https://orcid.org/0000-0002-8916-6749
Nanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to systematically evaluate the effect of Chinese herbal medicine (CHM) for treating allergic rhinitis in children. We reviewed relevant studies retrieved from the following databases: MEDLINE (PubMed), Embase, Cochrane Central Register of Controlled Trials, Chinese National Knowledge Infrastructure, the Cqvip Database, and the Wanfang Database. The analysis was conducted by Cochrane software Revman 5.3. Nineteen randomized, controlled trials were included. Meta-analysis showed that CHM had advantages in the efficacy rate (odds ratio [OR] 3.32; 95% confidence interval [CI], 2.32-4.76), recurrence rate (OR 0.30; 95% CI, 0.18-0.49), scores of symptoms, such as sneezing (mean difference [MD] -1.24; 95% CI, -2.33 to -0.14), running nose (MD -1.32; 95% CI, -2.58 to -0.05), and nasal congestion (MD -0.70; 95% CI, -1.05 to -0.36), but not nasal itching (MD -1.37; 95% CI, -3.96 to 1.22), compared with controls. CHM could also effectively decrease immunoglobulin E levels (MD -46.01, 95% CI, -57.53 to -34.48). The current evidence suggests that CHM is more effective in treating allergic rhinitis in children compared with controls. CHM may also decrease the recurrence and level of immunoglobulin E, and improve symptoms such as sneezing, running nose, and nasal congestion, compared with controls.

Indexed as

BiomarkersChildDrugs, Chinese HerbalHumansImmunoglobulin EMedicine, Chinese TraditionalRandomized Controlled Trials as TopicRhinitis, AllergicTreatment OutcomeBiomarkersDrugs, Chinese HerbalImmunoglobulin EAllergic rhinitischildrenChinese herbal medicineimmunoglobulin Emeta-analysisrandomized controlled trial

Identifiers

PMID30084286
PMCPMC6166336
OpenAlexW2886694106

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.