Evidence map›Paper›PMID 30084098›Full record

ArticleIndian journal of pediatrics2019

Effectiveness of Topical Application of Honey on Oral Mucosa of Children for the Management of Oral Mucositis Associated with Chemotherapy.

Rai Singh, Sunita Sharma, Sukhwinder Kaur, Bikash Medhi, Amita Trehan, Sunil Kumar Bijarania

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In one paragraph

Article in Indian journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Prophylactic and therapeutic effects of honey on radiochemotherapy-induced mucositis: a meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Its Oral Right, Honey!Indian journal of pediatrics · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rai SinghDepartment of Public Health Nursing, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. raisthory0777@gmail.com.
Sunita SharmaNational Institute of Nursing Education, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Sukhwinder KaurNational Institute of Nursing Education, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Bikash MedhiDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Amita TrehanHematology/Oncology Unit, Department of Pediatrics, Advance Pediatric Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Sunil Kumar BijaraniaDepartment of Neonatology Nursing, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effectiveness of topical application of honey on Oral Mucositis (OM) associated with chemotherapy.

methodsAn observational blind study is performed upon a sample of 100 children receiving chemotherapy who developed oral mucositis. All children are divided into two groups (control and experimental) who received different regimens. Both groups received routine practice of analgesic and antiseptic gel application whereas children in experimental group also received the topical application of honey on oral mucosa for the management of OM. All children are monitored from the day they developed oral mucositis until the subsidence of signs and symptoms of oral mucositis. The severity of OM was assessed with WHO-STC (Stomatitis Toxicity Criteria) scale by a observer blind.

resultsThere was statistically significant difference in reduction of severity of OM in both groups of children (p < 0.01). The duration of management of OM was significantly small in the experimental group (median 4 d, IQR: 4-6 d) as compared to the control group (median 6 d, IQR: 6-8 d) (p < 0.01).

conclusionsThe topical application of honey on oral mucosa was effective in reducing the severity and duration of management of chemotherapy induced oral mucositis (CIOM; p < 0.05) and that means honey is a good quality product with rich nutritious value and would be a pleasant, simple and cost-effective modality for the management of oral mucositis associated with chemotherapy.

Indexed as

Drug TherapyHoneyAntineoplastic AgentsChildDrug-Related Side Effects and Adverse ReactionsHumansMouth MucosaNeoplasmsPilot ProjectsStomatitisAntineoplastic AgentsChemotherapyChildrenHoneyOral mucositis

Identifiers

PMID30084098
OpenAlexW2885910318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.