Evidence map›Paper›PMID 30084034›Full record

ArticleParasitology research2018

A putative calcium-ATPase of the secretory pathway family may regulate calcium/manganese levels in the Golgi apparatus of Entamoeba histolytica.

Mario A Rodríguez, Aarón Martínez-Higuera, Martha I Valle-Solis, Mario Hernandes-Alejandro, Bibiana Chávez-Munguía, Ana H Figueroa-Gutiérrez, Andrés Salas-Casas

Abstract read
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In one paragraph

Article in Parasitology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. AnGenes · 2019
    Article
  6. A Calcium/Cation Exchanger Participates in the Programmed Cell Death andFrontiers in cellular and infection microbiology · 2018
    Article
  7. Mechanism of the Passage ofIranian journal of parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Mario A RodríguezDepartamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del IPN, Mexico City, Mexico.
Aarón Martínez-HigueraDepartamento de Física, Universidad de Sonora, Hermosillo, Sonora, Mexico.
Martha I Valle-SolisDepartamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del IPN, Mexico City, Mexico.
Mario Hernandes-AlejandroDepartamento de Bioingeniería, Unidad Profesional Interdisciplinaria de Biotecnología del Instituto Politécnico Nacional (UPIBI-IPN), Mexico City, Mexico.
Bibiana Chávez-MunguíaDepartamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del IPN, Mexico City, Mexico.
Ana H Figueroa-GutiérrezInstituto de Ciencias de la Salud, Área Académica de Gerontología, Universidad Autónoma del Estado de Hidalgo, Ex Hacienda la Concepción, s/n; Carretera Actopan-Tilcuautla, San Agustín Tlaxiaca, Hidalgo, Mexico.
Andrés Salas-CasasInstituto de Ciencias de la Salud, Área Académica de Gerontología, Universidad Autónoma del Estado de Hidalgo, Ex Hacienda la Concepción, s/n; Carretera Actopan-Tilcuautla, San Agustín Tlaxiaca, Hidalgo, Mexico. andres_salas15@yahoo.com.mx.
Center for Research and Advanced Studies of the National Polytechnic Institute · MXInstituto Politécnico Nacional · MXUniversidad Anáhuac · MXUniversidad Autónoma del Estado de Hidalgo · MXUniversidad de Sonora · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium regulates many cellular processes in protozoa, including growth, differentiation, programmed cell death, exocytosis, endocytosis, phagocytosis, fusion of the endosomes of distinct stages with phagosomes, fusion of phagosomes with lysosomes, and recycling the membrane. In Entamoeba histolytica, the protozoa responsible for human amoebiasis, calcium ions are essential for signaling pathways that lead to growth and development. In addition, calcium is crucial in the modulation of gene expression in this microorganism. However, there is scant information about the proteins responsible for regulating calcium levels in this parasite. In this work, we characterized a protein of E. histolytica that shows a close phylogenetic relationship with Ca

Indexed as

AnimalsCalciumCalcium-Transporting ATPasesEndosomesEntamoeba histolyticaEntamoebiasisGolgi ApparatusHumansIonsLysosomesManganeseMicroscopy, ImmunoelectronPhagocytosisPhagosomesPhylogenyVacuolesCalciumCalcium-Transporting ATPasesIonsManganeseCalcium-ATPasesEntamoeba histolyticaGolgi apparatusSPCA

Identifiers

PMID30084034
OpenAlexW2887379469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.