ArticleJournal of preventive medicine and hygiene2018
Healthcare-associated Clostridium difficile infection: role of correct hand hygiene in cross-infection control.
Article in Journal of preventive medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Safety and efficacy of fecal microbiota transplantation versus antibiotics for treating clostridioides difficile infection: systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Pooled it
- Multimodal Hand Hygiene Interventions and Clinical Healthcare-Associated Infection Outcomes in Acute Care Hospitals: A Systematic Review of Quasi-Experimental Studies.Journal of clinical medicine · 2026Review
- Impact of enteral feeding strategies on nosocomialFrontiers in nutrition · 2026Article
- The Role ofMicroorganisms · 2025Review
- Review
- Rinse, gel, and foam - is there any evidence for a difference in their effectiveness in preventing infections?Antimicrobial resistance and infection control · 2024Review
- Harnessing of Artificial Intelligence for the Diagnosis and Prevention of Hospital-Acquired Infections: A Systematic Review.Diagnostics (Basel, Switzerland) · 2024Review
- A Real-World Study on the Clinical Characteristics, Outcomes, and Relationship between Antibiotic Exposure andAntibiotics (Basel, Switzerland) · 2024Article
- Comparing the impact of two contact isolation modes for hospitalised patients with Clostridioides difficile infection on the quality of care.Journal of clinical nursing · 2023Article
- Role of diagnostic stewardship in reducing healthcare-facility-onsetAntimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Transmission of SARS-CoV-2 within households: a remote prospective cohort study in European countries.European journal of epidemiology · 2022Article
- Risk of Healthcare-AssociatedGastro hep advances · 2022Review
- Correlation between antibiotic consumption and the incidence of healthcare facility-onset Clostridioides difficile infection: a retrospective chart review and analysis.Antimicrobial resistance and infection control · 2021Article
- Opportunities for Nanomedicine inAntibiotics (Basel, Switzerland) · 2021Review
- [Level of Complete Knowledge on Five Moments of Hand Hygiene among Nurses Working at Integrated Nursing Care Service Wards].Journal of Korean Academy of Nursing · 2021Article
- Level of Knowledge of Medical Staff on the Basis of the Survey in Terms of Risk Management, Associated withInternational journal of environmental research and public health · 2021Article
- Article
- Has the COVID 19 Virus Changed Adherence to Hand Washing among Healthcare Workers?Behavioral sciences (Basel, Switzerland) · 2021Article
- Association of Visitor Contact Precautions With Estimated Hospital-Onset Clostridioides difficile Infection Rates in Acute Care Hospitals.JAMA network open · 2021Article
- Midwifery and Nursing Strategies to protect against COVID-19 During the Third Trimester of Pregnancy.Midwifery · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionClostridium difficile (CD) is the most common cause of health-care-associated infectious diarrhea with increasing incidence and severity in recent years. The main cause of hospital's acquired cross infections can be attributed to incorrect hand hygiene. We described the epidemiology of CD infection (CDI) in a teaching hospital in Southern Italy during a two years surveillance period and evaluated the health-care workers compliance to hand hygiene.
methodsCDI Incidence rates were calculated as the number of patients with positive C. difficile toxin assay per 10,000 patient-days. Compliance with hand hygiene was the ratio of the number of performed actions to the number of opportunities observed. Approximately 400 Hand Hygiene (HH) opportunities/year /ward were observed. We finally checked out if any correlation could be found.
resultsFrom January 2015 to December 2016 a total number of 854 CD determinations were performed in patients with clinical symptoms of diarrhea. The search for toxins A and B was positive in 175 cases (21,2%), confirming the diagnosis of CDI. Compliance to hand hygiene was significantly inversely associated with the number of CDIs: the lower the compliance of health-care workers with hand hygiene the higher was the number of cases of CDIs (p = 0.003).
conclusionsAccording to our results proper handwashing of health-care workers appears to be a key intervention in interrupting CD cross infections regardless of age and type of department in which the patient is admitted.
Indexed as
Identifiers
30083622PMC6069405W2884548949What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.