Evidence map›Paper›PMID 30083617›Full record

ArticleJournal of preventive medicine and hygiene2018

Hexavalent vaccines: characteristics of available products and practical considerations from a panel of Italian experts.

A Orsi, C Azzari, E Bozzola, G Chiamenti, G Chirico, S Esposito, F Francia, P Lopalco, R Prato, R Russo and 2 more

Abstract read
In one paragraph

Article in Journal of preventive medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Review
  13. DTaP-IPV-HepB-Hib Vaccine (HexyonPaediatric drugs · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

A OrsiDepartment of Health Sciences, University of Genoa, "Ospedale Policlinico San Martino IRCCS" Teaching Hospital, Genoa, Italy.
C AzzariPediatric Immunology Unit "Anna Meyer" Hospital, University of Florence, Italy.
E BozzolaBambino Gesù Children Hospital, Pediatric and Infectious Diseases Unit, Rome, Italy.
G ChiamentiItalian Federation of Family Paediatricians (FIMP), Verona, Italy.
G ChiricoNeonatal Intensive Care Unit, ASST Spedali Civili, Children Hospital of Brescia, Italy.
S EspositoPediatric Clinic, Department of Surgical and Biomedical Sciences, University of Perugia, Italy.
F FranciaItalian Society of Hygiene, Preventive Medicine and Public Health (SitI) and Department of Public Health, Local Health Authority of Bologna, Italy.
P LopalcoHygiene and Epidemiology section, Department of Translational Research, New Technologies in Medicine and Surgery, University of Pisa, Italy.
R PratoDepartment of Medical and Surgical Sciences, University of Foggia, Italy.
R RussoMaternity and Pediatrics Services, Local Health Authority of Benevento, Italy.
A VillaniBambino Gesù Children Hospital, Pediatric and Infectious Diseases Unit, Rome, Italy.
E FrancoDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combination vaccines represent a valuable technological innovation in the field of infectious disease prevention and public health, because of their great health and economic value from the individual, societal, and healthcare system perspectives. In order to increase parents' and healthcare professionals' confidence in the vaccination programs and maintain their benefits to society, more information about the benefits of innovative vaccination tools such as combination vaccines is needed. Purpose of this work is an examination of available hexavalent vaccines, that protect against Diphtheria, Tetanus, Pertussis, Poliomyelitis, Hepatitis B and Haemophilus influenzae type b infections. From the epidemiological updates of vaccine preventable diseases to the vaccine development cycle, from the immunogenicity of antigenic components to the safety and co-administration with other vaccines, several aspects of available hexavalent vaccines are discussed and deepened. Also a number of practical considerations on schedules, age of employment, strategies for vaccination recovery, vaccination in at-risk births are issued, based on the recommendations of Italian Ministry of Health, Italian Society of Pharmacology (SIF), Italian Society for Pediatrics (SIP), Italian Federation of Family Paediatricians (FIMP) and Italian Society of Hygiene, Preventive Medicine and Public Health (SItI).

Indexed as

Communicable Disease ControlConsensusPatient SafetyDiphtheria-Tetanus-Pertussis VaccineDrug IndustryFemaleHepatitis B VaccinesHumansItalyMalePoliovirus Vaccine, InactivatedPregnancyDiphtheria-Tetanus-Pertussis VaccineHepatitis B VaccinesHexavacPoliovirus Vaccine, InactivatedCo-administrationCombination vaccinesHexavalent vaccinesSafetyVaccine manufacturing

Identifiers

PMID30083617
PMCPMC6069402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.