ArticleScience advances2018
Chiral switching in biomineral suprastructures induced by homochiral l-amino acid.
Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 60 citations in OpenAlex.
- General Synthesis of Chiral Mesostructured Carbonates Using Chiral Vicinal Polyhydroxy Molecules.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Recent Advances in Application of Circularly Polarized Luminescence Probes toward Bioimaging Technology.Chemical & biomedical imaging · 2026Review
- Long-Range Spin Transport in Chiral Gold.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Size Control of Biomimetic Curved-Edge Vaterite with Chiral Toroid Morphology via Sonochemical Synthesis.Biomimetics (Basel, Switzerland) · 2024Article
- Mechanosensitive non-equilibrium supramolecular polymerization in closed chemical systems.Nature communications · 2023Article
- Biomimetic Self-Assembled Chiral Inorganic Nanomaterials: A New Strategy for Solving Medical Problems.Biomimetics (Basel, Switzerland) · 2022Review
- Liquid crystal-templated chiral nanomaterials: from chiral plasmonics to circularly polarized luminescence.Light, science & applications · 2022Review
- Hierarchical self-assembly into chiral nanostructures.Chemical science · 2022Review
- Liquid-Liquid Phase Separation in Nucleation Process of Biomineralization.Frontiers in chemistry · 2022Review
- Chiral Tartaric Acid Improves Fracture Toughness of Bioactive Brushite-Collagen Bone Cements.ACS applied bio materials · 2020Article
- Homochirality in biomineral suprastructures induced by assembly of single-enantiomer amino acids from a nonracemic mixture.Nature communications · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
How homochiral l-biomolecules in nature induce a chiral switch in biomineralized architectures is unknown, although chiral switching is common in many calcium carbonate-hardened structures found in marine and terrestrial organisms. We created hierarchically organized, chiral biomineral structures of calcium carbonate, whose chirality can be switched by a single l-enantiomer of an amino acid. The control of this chiral switching involves two stages: a calcium carbonate (vaterite) platelet layer inclination stage, followed by a platelet layer rotation stage, the latter stage being responsible for successional chiral switching events within the biomineralized structures. The morphology of the synthesized chiral vaterite structures remarkably resembles pathologic chiral vaterite otoconia found in the human inner ear. In general, these findings describe how a single-enantiomer amino acid might contribute to biomineral architectures having more than one chirality as is commonly seen in biology, and more specifically, they suggest how pathologic chiral malformations may arise in humans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.