Evidence map›Paper›PMID 30083565›Full record

ArticleNeurogenesis (Austin, Tex.)2018

Role of neoblasts in the patterned postembryonic growth of the platyhelminth

Maria Del Mar De Miguel-Bonet, Sally Ahad, Volker Hartenstein

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurogenesis (Austin, Tex.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maria Del Mar De Miguel-BonetDepartment of Molecular Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Sally AhadDepartment of Molecular Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Volker HartensteinDepartment of Molecular Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
University of California, Los Angeles · US

Funding

Lineage-associated wiring properties of Drosphila brain neuronsR01NS054814 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HARTENSTEIN, VOLKER, LOUIS, MATTHIEU R. P. J. C. G. · 2006 to 2025
$6.6M
NINDS NIH HHS R01 NS054814
6 · The paper itself

Abstract

Neoblasts are motile pluripotent stem cells unique to the flatworm phyla Platyhelminthes and Acoela. The role of neoblasts in tissue regeneration has received much attention in recent studies. Here we review data pertinent to the structure and embryonic origin of these stem cells, and their participation in normal cell turnover. Next, we present data proving that neoblasts also account for the addition of cells during postembryonic growth. Bromodeoxyuridine (BrdU) pulse chase experiments demonstrate that the incorporation of neoblast-derived cells into the different tissues of the juvenile worm follows a stereotyped pattern, whereby cells within the parenchymal layer (muscle, gland) incorporate new cells most rapidly, followed by the epidermal domain surrounding the mouth, dorsal epidermis, and, lastly, the nervous system.

Indexed as

developmentneoblastneurogenesisPlatyhelminthesproliferation

Identifiers

PMID30083565
PMCPMC6067875
OpenAlexW2799380502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.