Evidence map›Paper›PMID 30083449›Full record

ArticlePeerJ2018

BTW-Bioinformatics Through Windows: an easy-to-install package to analyze marker gene data.

Daniel Morais, Luiz F W Roesch, Marc Redmile-Gordon, Fausto G Santos, Petr Baldrian, Fernando D Andreote, Victor S Pylro

Abstract read
In one paragraph

Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Frontiers in genetics · 2020
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel MoraisInstitute of Microbiology of the CAS, Prague, Czech Republic.
Luiz F W RoeschCentro para Pesquisa Interdisciplinar em Biotecnologia, Universidade Federal do Pampa, São Gabriel, Rio Grande do Sul, Brazil.
Marc Redmile-GordonNatural England, Sheffield, United Kingdom.
Fausto G SantosBiosystems Informatics and Genomics, Instituto René Rachou, Belo Horizonte, Brazil.
Petr BaldrianInstitute of Microbiology of the CAS, Prague, Czech Republic.
Fernando D AndreoteSoil Department, "Luiz de Queiroz" College of Agriculture - ESALQ/USP, Piracicaba, São Paulo, Brazil.
Victor S PylroSoil Department, "Luiz de Queiroz" College of Agriculture - ESALQ/USP, Piracicaba, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in Next-Generation Sequencing (NGS) make comparative analyses of the composition and diversity of whole microbial communities possible at a far greater depth than ever before. This brings new challenges, such as an increased dependence on computation to process these huge datasets. The demand on system resources usually requires migrating from Windows to Linux-based operating systems and prior familiarity with command-line interfaces. To overcome this barrier, we developed a fully automated and easy-to-install package as well as a complete, easy-to-follow pipeline for microbial metataxonomic analysis operating in the Windows Subsystem for Linux (WSL)-Bioinformatics Through Windows (BTW). BTW combines several open-access tools for processing marker gene data, including 16S rRNA, bringing the user from raw sequencing reads to diversity-related conclusions. It includes data quality filtering, clustering, taxonomic assignment and further statistical analyses, directly in WSL, avoiding the prior need of migrating from Windows to Linux. BTW is expected to boost the use of NGS amplicon data by facilitating rapid access to a set of bioinformatics tools for Windows users. Moreover, several Linux command line tools became more reachable, which will enhance bioinformatics accessibility to a wider range of researchers and practitioners in the life sciences and medicine. BTW is available in GitHub (https://github.com/vpylro/BTW). The package is freely available for noncommercial users.

Indexed as

16S rRNAMarker geneMetataxonomicsMicrobiomeWindows

Identifiers

PMID30083449
PMCPMC6074753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.