Evidence map›Paper›PMID 30083338›Full record

ArticleUnited European gastroenterology journal2018

Screening colonoscopy and risk of adverse events among individuals undergoing fecal immunochemical testing in a population-based program: A nested case-control study.

Eunate Arana-Arri, Natale Imaz-Ayo, Mari Jose Fernández, Isabel Idigoras, Isabel Bilbao, Luis Bujanda, Fidencio Bao, Enrique Ojembarrena, Ines Gil, Iñaki Gutiérrez-Ibarluzea and 1 more

Abstract read
In one paragraph

Article in United European gastroenterology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Risk of Colorectal Cancer and Colorectal Cancer Mortality Beginning One Year after a Negative Fecal Occult Blood Test, among Screen-Eligible 76- to 85-Year-Olds.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eunate Arana-ArriBiocruces Health Research Institute, Barakaldo, Spain.
Natale Imaz-AyoBiocruces Health Research Institute, Barakaldo, Spain.
Mari Jose FernándezColorectal Cancer Screening Programme Coordination Center, Bilbao, Spain.
Isabel IdigorasBiocruces Health Research Institute, Barakaldo, Spain.
Isabel BilbaoBiocruces Health Research Institute, Barakaldo, Spain.
Luis BujandaBiodonostia Health Research Institute, Donostia, Spain.
Fidencio BaoBiocruces Health Research Institute, Barakaldo, Spain.
Enrique OjembarrenaBiocruces Health Research Institute, Barakaldo, Spain.
Ines GilBiodonostia Health Research Institute, Donostia, Spain.
Iñaki Gutiérrez-IbarluzeaOsteba, Basque Office for Health Technology Assessment, Gasteiz, Spain.
Isabel PortilloBiocruces Health Research Institute, Barakaldo, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundScreening by means of biennial fecal occult blood test has provided a reduction in overall colorectal cancer mortality. Notwithstanding, we should not underestimate the harms that it can produce.

aimThe aim of this article is to identify the independent risk factors of complications after a screening colonoscopy.

methodsA six-year, nested case-control study was conducted. Mortality/complications within 30 days after colonoscopy were registered and its predictors identified through logistic regression.

resultsAfter 39,254 colonoscopies, the complication rate was 1.0%. Independent predictors were sex (OR 1.68 for men; CI 95% 1.18-2.39), ASA physical status classification system (OR 1.73 for ASA II-III; CI 95% 1.53-3.69), history of abdominal surgery (OR 2.37; CI 95% 1.72-4.08), diverticulosis (OR 2.89; CI 95% 1.94-4.30), inadequate cleansing (OR 29.35; CI 95% 6.52-132.17), detection of advanced neoplasia (AN) (OR 4.92; CI 95% 3.29-7.36), detection of stage I adenocarcinoma (OR 9.44; CI 95% 4.46-20.0), polyps in right colon OR 2.27 CI 95% 1.38-3.74) and complex polypectomy (OR 2.00; CI 95% 1.25-3.20). The logistic model explained 82% of the complications (CI 95% 0.798-0.854,

conclusionsColonoscopy, with or without removal of a lesion, is an invasive procedure with a non-deniable risk of major complications. Factors like inadequate cleansing or detection of AN are determinants. Therefore, it is vital to know which aspects predict their appearance to implement countermeasures.

Indexed as

Colorectal cancercomplicationfecal immunochemical testindependent risk factorsscreening colonoscopy

Identifiers

PMID30083338
PMCPMC6068784

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.