Evidence map›Paper›PMID 30083309›Full record

ArticleJournal of tissue engineering

Near-infrared laser-mediated drug release and antibacterial activity of gold nanorod-sputtered titania nanotubes.

Kyoung-Suk Moon, Young-Bum Park, Ji-Myung Bae, Seunghan Oh

Open access · goldAbstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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  7. Topographical nanostructures for physical sterilization.Drug delivery and translational research · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kyoung-Suk MoonDepartment of Dental Biomaterials and Institute of Biomaterial and Implant, College of Dentistry, Wonkwang University, Iksan, Republic of Korea.
Young-Bum ParkDepartment of Prosthodontology, College of Dentistry, Yonsei University, Seoul, Republic of Korea.
Ji-Myung BaeDepartment of Dental Biomaterials and Institute of Biomaterial and Implant, College of Dentistry, Wonkwang University, Iksan, Republic of Korea.
Seunghan OhDepartment of Dental Biomaterials and Institute of Biomaterial and Implant, College of Dentistry, Wonkwang University, Iksan, Republic of Korea.ORCID https://orcid.org/0000-0002-7250-721X
Wonkwang University · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The infection control of implants is one of the hot issues in the field of medicine and dentistry. In this study, we prepared gold nanorod-sputtered titania nanotubes on titanium surface, which is the main component of implant material, and aimed to estimate the remote-controlled tetracycline release and resulting antibacterial effects of gold nanorod-sputtered titania nanotubes using near-infrared laser irradiation. Gold nanorods prepared by ion plasma sputtering (aspect ratio = 1:3) showed optical properties like those of chemically synthesized gold nanorods, exhibiting photothermal effects in the near-infrared region, as demonstrated using field-emission scanning electron microscopy, transmission electron microscopy, and diffuse ultraviolet-visible-near-infrared spectrophotometry. In addition, a 2 wt% tetracycline/polycaprolactone mixture was found to be the most suitable experimental group to demonstrate the biological compatibilities and antibacterial activities. The results of antibacterial agar diffusion tests and near-infrared-mediated tetracycline release tests in vivo confirmed that remote-controlled tetracycline elution using near-infrared laser irradiation was highly effective. Therefore, gold nanorod-sputtered titania nanotubes would be expected to enable the continued use of the photothermal therapy of gold nanorods and extend the limited use of titania showing photocatalytic activity only within the ultraviolet-to-near-infrared region.

Indexed as

antibacterial activityGold nanorodsnear-infrared lasertetracyclinetitania nanotubes

Identifiers

PMID30083309
PMCPMC6071157
OpenAlexW2883171475

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.