ArticleTheranostics2018
Microvesicles and ectosomes in angiogenesis and diabetes - message in a bottle in the vascular ocean.
Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Review
- Tissue-Derived Small Extracellular Vesicles: Emerging Regulators of Inter-Organ Crosstalk in Health and Disease.Metabolites · 2026Review
- Exomeres and supermeres: Current advances and perspectives.Bioactive materials · 2025Review
- Diabetes current and future translatable therapies.Endocrine · 2024Review
- Current understanding of the role of Adipose-derived Extracellular Vesicles in Metabolic Homeostasis and Diseases: Communication from the distance between cells/tissues.Theranostics · 2020Review
- DR-region of NaTheranostics · 2020Article
- miR-27a regulates vascular remodeling by targeting endothelial cells' apoptosis and interaction with vascular smooth muscle cells in aortic dissection.Theranostics · 2019Article
- Rho-Associated Coiled-Coil Kinase (ROCK) in Molecular Regulation of Angiogenesis.Theranostics · 2018Review
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pathogenesis of diabetes involves dysregulated gene expression on a pre- and posttranscriptional level. One key mechanism in the development and progression of diabetes is thought being a dysregulation of signalling mediators such as microRNAs. These microRNAs interfere with pathophysiological reactions in diabetes by affecting gene transcription, insulin resistance and endothelial dysfunction. Here, in this current issue, Stępień et al. analysed ectosomal miRNA patterns in patients with type 2 diabetes mellitus (T2DM) using different analytical techniques. The focus of the current analysis was to characterize pro- and anti-angiogenic signalling effects of ectosomal miRNAs revealing important pathophysiologic mechanisms and signalling in T2DM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.