Evidence map›Paper›PMID 30083127›Full record

ArticleFrontiers in neurology2018

Efficacy, Retention, and Tolerability of Brivaracetam in Patients With Epileptic Encephalopathies: A Multicenter Cohort Study From Germany.

Laurent M Willems, Astrid Bertsche, Frank Bösebeck, Frauke Hornemann, Ilka Immisch, Karl M Klein, Susanne Knake, Rhina Kunz, Gerhard Kurlemann, Lisa Langenbruch and 9 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Efficacy and safety of Brivaracetam as adjunctive therapy in pediatric epilepsy: A systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
  2. Pooled it
  3. Review
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  5. Observational
  6. Review
  7. Observational
  8. Article
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  13. Prevalence, risk factors and therapeutic aspects of injuries and accidents in women with epilepsy.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 9 institutions in 1 country.

Laurent M WillemsEpilepsy Center Frankfurt Rhine-Main and Department of Neurology, Goethe University Frankfurt, Frankfurt, Germany.
Astrid BertscheDepartment of Neuropediatrics, University of Rostock, Rostock, Germany.
Frank BösebeckEpilepsy Center Rotenburg, Agaplesion Diakonieklinikum Rotenburg, Rotenburg, Germany.
Frauke HornemannCentre of Pediatric Research, Hospital for Children and Adolescents, Leipzig, Germany.
Ilka ImmischEpilepsy Center Hessen and Department of Neurology, Philipps-University, Marburg, Germany.
Karl M KleinEpilepsy Center Frankfurt Rhine-Main and Department of Neurology, Goethe University Frankfurt, Frankfurt, Germany.
Susanne KnakeEpilepsy Center Hessen and Department of Neurology, Philipps-University, Marburg, Germany.
Rhina KunzEpilepsy Center Greifswald and Department of Neurology, Ernst-Moritz-Arndt-University, Greifswald, Germany.
Gerhard KurlemannDepartment of Neuropediatrics, Westfälische Wilhelms-University, Münster, Germany.
Lisa LangenbruchEpilepsy Center Münster-Osnabrück, Department of Neurology with Institute of Translational Neurology - Epileptology, Westfälische Wilhelms-University, Münster, Germany.
Gabriel MöddelEpilepsy Center Münster-Osnabrück, Department of Neurology with Institute of Translational Neurology - Epileptology, Westfälische Wilhelms-University, Münster, Germany.
Karen Müller-SchlüterEpilepsy Center for Children, University Hospital Neuruppin, Brandenburg Medical School, Neuruppin, Germany.
Felix von PodewilsEpilepsy Center Greifswald and Department of Neurology, Ernst-Moritz-Arndt-University, Greifswald, Germany.
Philipp S ReifEpilepsy Center Frankfurt Rhine-Main and Department of Neurology, Goethe University Frankfurt, Frankfurt, Germany.
Bernhard J SteinhoffKork Epilepsy Center, Kehl-Kork, Germany.
Isabel SteinigEpilepsy Center Frankfurt Rhine-Main and Department of Neurology, Goethe University Frankfurt, Frankfurt, Germany.
Felix RosenowEpilepsy Center Frankfurt Rhine-Main and Department of Neurology, Goethe University Frankfurt, Frankfurt, Germany.
Susanne Schubert-BastEpilepsy Center Frankfurt Rhine-Main and Department of Neurology, Goethe University Frankfurt, Frankfurt, Germany.
Adam StrzelczykEpilepsy Center Frankfurt Rhine-Main and Department of Neurology, Goethe University Frankfurt, Frankfurt, Germany.
Goethe University Frankfurt · DEUniversity of Münster · DEPhilipps University of Marburg · DEUniversität Greifswald · DEAgaplesion Diakonieklinikum Rotenburg · DEDiakonie Kork · DEMedizinische Hochschule Brandenburg Theodor Fontane · DEUniversity Hospital Leipzig · DEUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anticonvulsantsepilepsyepileptic encephalopathieslevetiracetamseizure

Identifiers

PMID30083127
PMCPMC6064736
OpenAlexW2811592420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.