ArticleClinical medicine insights. Case reports2018
Graves Disease Causing Pancytopenia: Case Report and Literature Review.
Article in Clinical medicine insights. Case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 12 citations in OpenAlex.
- Pharmacovigilance and clinical insights into perindopril-induced thrombocytopenia: a case report of diagnostic challenges and therapeutic alternatives.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Article
- Rare Autoimmune Pancytopenia Due to Graves Disease.JCEM case reports · 2025Article
- Methimazole-Induced Pancytopenia in a Patient with Graves' Disease: A Case Report and Literature Review.Current drug safety · 2025Review
- Hyperthyroidism crisis and complex pancytopenia: A case report.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Article
- Graves' disease with pancytopenia: A rare case report.Clinical case reports · 2024Article
- Article
- Pre-treatment Neutropenia in Children and Adolescents with Autoimmune HyperthyroidismJournal of clinical research in pediatric endocrinology · 2021Article
- Graves' hyperthyroidism-related pancytopenia: a case report with literature review.Hormones (Athens, Greece) · 2021Review
- Peripheral blood picture and aminotransferase activity in children with newly diagnosed Graves' disease at baseline and after the initiation of antithyroid drug therapy.Central-European journal of immunology · 2019Article
- Graves' Disease with Pancytopenia and Hepatic Dysfunction: A Rare Case Presentation.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
- PANCYTOPENIA AND LYMPHOID ORGAN HYPERPLASIA IN A PATIENT WITH GRAVES DISEASE: RESPONSE TO ANTITHYROID DRUG THERAPY.AACE clinical case reportsArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGraves disease or other causes of thyrotoxicosis are frequently associated with cytopenia. Although anemia is the most common, other cell lineage can be affected. Pancytopenia is a rare complication of thyrotoxicosis. CASE PRESENTATION: We report a case of a 33-year-old Chinese man who presented a nonsevere pancytopenia in the context of a newly diagnosed Graves disease. Restauration of euthyroid state led to progressive correction of pancytopenia.
conclusionsLiterature review shows other rare cases of pancytopenia. It is usually nonsevere with just extremely rare cases of transfusion reported. Evolution was always favorable after achievement of euthyroid state. Its mechanism remains poorly understood, especially because those patients have no vitamin or iron deficiency. The exact physiopathological process remains unclear but 2 causes seem to overlap: reduced production of hematopoietic cells from the bone marrow and increased destruction or sequestration of mature hematopoietic cells. Despite unclear mechanism, the presence of hematologic abnormalities including pancytopenia must not be considered as a contraindication to antithyroid drug therapy.
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