Evidence map›Paper›PMID 30083055›Full record

ArticleBreast cancer : basic and clinical research2018

Epithelial-Mesenchymal Transition Markers in Breast Cancer and Pathological Responseafter Neoadjuvant Chemotherapy.

Shaimaa Elzamly, Nabeel Badri, Osvaldo Padilla, Alok Kumar Dwivedi, Luis A Alvarado, Matthew Hamilton, Nabih Diab, Crosby Rock, Ahmed Elfar, Marwa Teleb and 2 more

Open access · goldAbstract read
In one paragraph

Article in Breast cancer : basic and clinical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
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  3. 3‑Phenethyl-2-phenylquinazolin-4(3ACS pharmacology & translational science · 2025
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  9. Review
  10. Article
  11. Article
  12. Revisiting Epithelial Carcinogenesis.International journal of molecular sciences · 2022
    Article
  13. Article
  14. Article
  15. Review
  16. Recent advances in liposome formulations for breast cancer therapeutics.Cellular and molecular life sciences : CMLS · 2021
    Review
  17. Article
  18. Proteomics and its applications in breast cancer.American journal of cancer research · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Shaimaa ElzamlyDepartment of Pathology, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Nabeel BadriDepartment of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Osvaldo PadillaDepartment of Pathology, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Alok Kumar DwivediDivision of Biostatistics and Epidemiology, Department of Biomedical Sciences, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Luis A AlvaradoDivision of Biostatistics and Epidemiology, Department of Biomedical Sciences, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Matthew HamiltonPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Nabih DiabPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Crosby RockPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Ahmed ElfarDepartment of Nephrology, UT Southwestern Medical Center and Parkland Memorial Hospital, Dallas, TX, USA.
Marwa TelebDepartment of Internal Medicine VA Hospital of North Texas, Dallas, TX, USA.
Luis SanchezDepartment of Internal Medicine VA Hospital of North Texas, Dallas, TX, USA.
Zeina NahlehDepartment of Hematology-Oncology, Maroone Cancer Center, Cleveland Clinic Florida, Weston, FL, USA.
Texas Tech University Health Sciences Center · USTexas Tech University · USCleveland Clinic Florida · USParkland Memorial Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between pathologic complete response (pCR) following to neoadjuvant chemotherapy (NAC) and the improved survival in breast cancer has been previously reported. The aim of this study was is to explore the expression of several biomarkers described during epithelial-mesenchymal transition (EMT) and the achievement of pCR in different molecular subtypes of breast cancer. We identified archived pathology tissue from patients with breast cancer who received NAC during the year 2014. We performed immunohistochemical analysis of vimentin, nuclear factor κB (NF-κB), epidermal growth factor receptor (EGFR), E-cadherin, estrogen receptor (ER), progesterone receptor, and Her2neu and studied the association between the expression of these markers and pCR. A Fisher exact test for categorical cofactors, an unpaired

Indexed as

E-cadherinEGFREpithelial-mesenchymal transition (EMT)NF-κBpathological responsetriple-negative breast cancertumor markervimentin

Identifiers

PMID30083055
PMCPMC6071152
OpenAlexW2886436007

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.