Evidence map›Paper›PMID 30082917›Full record

ArticleScientific reports2018

Molecular characterization of echovirus 12 strains isolated from healthy children in China.

Hongbo Liu, Jie Zhang, Yilin Zhao, Haihao Zhang, Keqin Lin, Hao Sun, Xiaoqin Huang, Zhaoqing Yang, Shaohui Ma

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Genetic Characteristics and Phylogeographic Dynamics of Echovirus.Journal of microbiology (Seoul, Korea) · 2023
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hongbo LiuInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, 650118, PR China.
Jie ZhangInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, 650118, PR China.
Yilin ZhaoInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, 650118, PR China.
Haihao ZhangInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, 650118, PR China.
Keqin LinInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, 650118, PR China.
Hao SunInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, 650118, PR China.
Xiaoqin HuangInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, 650118, PR China.
Zhaoqing YangInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, 650118, PR China. zyang@imbcams.com.cn.
Shaohui MaInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, 650118, PR China. shaohuima70@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human echovirus 12 (E-12) belongs to the enterovirus B species. To date, only one full-length genome sequence of E-12 (prototype strain Travis) is available in the GenBank database. This study determined the complete sequence of three E-12 strains, which were isolated from the stools of three healthy children in Yunnan, China, in 2013. We revealed that the three Yunnan E-12 strains had only 80.8-80.9% nucleotide identity and 96.4-96.8% amino acid identity with the Travis strain based on pairwise comparisons of the complete genome nucleotide and amino acid sequences. The three Yunnan strains shared 99.7% nucleotide identity and 99.1-99.5% amino acid similarity. Phylogenetic and similarity plot analyses showed that intertypic recombination occurred in the non-structural regions of the three Yunnan E-12 strains. This is the first report of the complete genome sequence of E-12 in China and it enriches the complete genome sequences of E-12 in the GenBank database.

Indexed as

Amino Acid SequenceChinaEnterovirus B, HumanGenome, ViralHumansPhylogenyRecombination, GeneticViral ProteinsWhole Genome SequencingViral Proteins

Identifiers

PMID30082917
PMCPMC6078983

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