Evidence map›Paper›PMID 30082898›Full record

ArticleNature methods2018

Single-DNA electron spin resonance spectroscopy in aqueous solutions.

Fazhan Shi, Fei Kong, Pengju Zhao, Xiaojun Zhang, Ming Chen, Sanyou Chen, Qi Zhang, Mengqi Wang, Xiangyu Ye, Zhecheng Wang and 6 more

Erratum issuedOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature methods, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 92 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Electron Spin Resonance at the Single-Molecule Scale.Angewandte Chemie (International ed. in English) · 2025
    Review
  5. Quantum relaxometry for detecting biomolecular interactions with single NV centers.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. A spin-mechanical quantum chip for exploring exotic interactions.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Biocompatible surface functionalization architecture for a diamond quantum sensor.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  20. Immunomagnetic microscopy of tumor tissues using quantum sensors in diamond.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 3 countries.

Fazhan ShiCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.ORCID http://orcid.org/0000-0003-3312-5566
Fei KongCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.ORCID http://orcid.org/0000-0002-5144-0909
Pengju ZhaoCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.
Xiaojun ZhangDepartment of Chemistry, University of Southern California, Los Angeles, CA, USA.
Ming ChenCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.
Sanyou ChenCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.
Qi ZhangCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.
Mengqi WangCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.
Xiangyu YeCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.
Zhecheng WangCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.
Zhuoyang QinCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.
Xing RongCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.
Jihu SuCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.
Pengfei WangCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China.
Peter Z QinDepartment of Chemistry, University of Southern California, Los Angeles, CA, USA. pzq@usc.edu.ORCID http://orcid.org/0000-0003-3967-366X
Jiangfeng DuCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China (USTC), Hefei, China. djf@ustc.edu.cn.ORCID http://orcid.org/0000-0001-8085-8012
University of Science and Technology of China · CNUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic resonance spectroscopy of single biomolecules under near-physiological conditions could substantially advance understanding of their biological function, but this approach remains very challenging. Here we used nitrogen-vacancy centers in diamonds to detect electron spin resonance spectra of individual, tethered DNA duplexes labeled with a nitroxide spin label in aqueous buffer solutions at ambient temperatures. This work paves the way for magnetic resonance studies on single biomolecules and their intermolecular interactions in native-like environments.

Indexed as

DNAElectron Spin Resonance SpectroscopySingle Molecule ImagingSolutionsWaterDNASolutionsWater

Identifiers

PMID30082898
OpenAlexW2883169450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.