Evidence map›Paper›PMID 30082844›Full record

ArticleNature communications2018

Low irradiance multiphoton imaging with alloyed lanthanide nanocrystals.

Bining Tian, Angel Fernandez-Bravo, Hossein Najafiaghdam, Nicole A Torquato, M Virginia P Altoe, Ayelet Teitelboim, Cheryl A Tajon, Yue Tian, Nicholas J Borys, Edward S Barnard and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Article
  2. Article
  3. Precision Labeling of Native Antibodies with Lock Coupling.Journal of the American Chemical Society · 2026
    Article
  4. Article
  5. Enhanced Single-Particle Upconversion Imaging via Energy Migration Boosting.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Significant Enhancement of the Upconversion Emission in Highly ErAngewandte Chemie (International ed. in English) · 2023
    Article
  15. Article
  16. Bioimaging with Upconversion Nanoparticles.Advanced photonics research · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bining TianThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Angel Fernandez-BravoThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Hossein NajafiaghdamDepartment of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, 94720, USA.
Nicole A TorquatoThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
M Virginia P AltoeThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Ayelet TeitelboimThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Cheryl A TajonThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Yue TianThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Nicholas J BorysThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Edward S BarnardThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.ORCID http://orcid.org/0000-0003-4736-0743
Mekhail AnwarDepartment of Radiation Oncology, University of California, San Francisco, San Francisco, CA, 94158, USA.
Emory M ChanThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA. emchan@lbl.gov.
P James SchuckThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA. p.j.schuck@columbia.edu.
Bruce E CohenThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA. becohen@lbl.gov.ORCID http://orcid.org/0000-0003-3655-3638

Funding

Visualizing endogenous ion channel activationR01NS096317 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI COHEN, BRUCE E, SACK, JON THOMAS · 2016 to 2019
$1.4M
DOE | SC | Basic Energy Sciences (BES) DE-AC02-05CH11231
6 · The paper itself

Abstract

Multiphoton imaging techniques that convert low-energy excitation to higher energy emission are widely used to improve signal over background, reduce scatter, and limit photodamage. Lanthanide-doped upconverting nanoparticles (UCNPs) are among the most efficient multiphoton probes, but even UCNPs with optimized lanthanide dopant levels require laser intensities that may be problematic. Here, we develop protein-sized, alloyed UCNPs (aUCNPs) that can be imaged individually at laser intensities >300-fold lower than needed for comparably sized doped UCNPs. Using single UCNP characterization and kinetic modeling, we find that addition of inert shells changes optimal lanthanide content from Yb

Identifiers

PMID30082844
PMCPMC6079005

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.