ArticleNature communications2018
Social interactions impact on the dopaminergic system and drive individuality.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed.
- Dynamic salience as a basis for behavioural meta-malleability.Royal Society open science · 2026Review
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- The Training Village: an open platform for continuous testing of rodents in cognitive tasks.bioRxiv : the preprint server for biology · 2026Article
- Epigenetic Regulation of Inflammation by Dopamine in Primary Human Macrophages.bioRxiv : the preprint server for biology · 2026Article
- Epigenetic regulation of inflammation by dopamine in primary human macrophages.Frontiers in immunology · 2026Article
- Dopaminergic neurons in the dorsal raphe nucleus may modulate social dominance in mice.Zoological research · 2025Article
- Article
- Continuous monitoring and machine vision reveals that developing gerbils exhibit structured social behaviors prior to the emergence of autonomy.PLoS biology · 2025Article
- How dopamine guides our social world.Pharmacological reviews · 2025Review
- Direct and indirect striatal projecting neurons exert strategy-dependent effects on decision-making.Science advances · 2025Article
- The 7 Muses of Neuro-Creative Cycle: How some patients with Parkinson's disease can unleash latent creativity.AIMS neuroscience · 2025Article
- How can ethology inform the neuroscience of fear, aggression and dominance?Nature reviews. Neuroscience · 2024Review
- Induction of territorial dominance and subordination behaviors in laboratory mice.Scientific reports · 2024Article
- The Involvement of the Ventral Tegmental Area in the Electroacupuncture Alleviation of Anxiety-Like Behaviors Induced by Chronic Restraint Stress in Mice.Neurochemical research · 2024Article
- Individualistic reward-seeking strategies that predict response to nicotine emerge among isogenic male mice living in a micro-society.PLoS biology · 2024Article
- Distinct dynamics and intrinsic properties in ventral tegmental area populations mediate reward association and motivation.Cell reports · 2024Article
- Female behavior drives the formation of distinct social structures in C57BL/6J versus wild-derived outbred mice in field enclosures.BMC biology · 2024Article
- The human neuropsychiatric risk gene Drd2 is necessary for social functioning across evolutionary distant species.Molecular psychiatry · 2024Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
Individuality is a striking feature of animal behavior. Individual animals differ in traits and preferences which shape their interactions and their prospects for survival. However, the mechanisms underlying behavioral individuation are poorly understood and are generally considered to be genetic-based. Here, we devised a large environment, Souris City, in which mice live continuously in large groups. We observed the emergence of individual differences in social behavior, activity levels, and cognitive traits, even though the animals had low genetic diversity (inbred C57BL/6J strain). We further show that the phenotypic divergence in individual behaviors was mirrored by developing differences in midbrain dopamine neuron firing properties. Strikingly, modifying the social environment resulted in a fast re-adaptation of both the animal's traits and its dopamine firing pattern. Individuality can rapidly change upon social challenges, and does not just depend on the genetic status or the accumulation of small differences throughout development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.