Evidence map›Paper›PMID 30082640›Full record

ArticleInternational journal of molecular sciences2018

Intra-Articular Formulation of GE11-PLGA Conjugate-Based NPs for Dexamethasone Selective Targeting-In Vitro Evaluation.

Enrica Chiesa, Silvia Pisani, Barbara Colzani, Rossella Dorati, Bice Conti, Tiziana Modena, Kevin Braekmans, Ida Genta

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Enrica ChiesaDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia (PV), Italy. enrica.chiesa01@universitadipavia.it.
Silvia PisaniDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia (PV), Italy. silvia.pisani01@universitadipavia.it.
Barbara ColzaniDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia (PV), Italy. barbara.colzani01@universitadipavia.it.
Rossella DoratiDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia (PV), Italy. rossella.dorati@unipv.it.
Bice ContiDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia (PV), Italy. bice.conti@unipv.it.ORCID 0000-0002-0034-2815
Tiziana ModenaDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia (PV), Italy. tiziana.modena@unipv.it.
Kevin BraekmansLaboratory of General Biochemistry and Physical Pharmacy, Ghent University, Ottergemsesteenweg 460, 9000 Gent, Belgium. Kevin.Braeckmans@UGent.be.ORCID 0000-0002-7993-6295
Ida GentaDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia (PV), Italy. ida.genta@unipv.it.
University of Pavia · ITGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selectively targeted nanoscale drug delivery systems have recently emerged as promising intravenously therapeutic option for most chronic joint diseases. Here, a newly synthetized dodecapeptide (GE11)-polylactide-

Indexed as

AnimalsChitosanDexamethasoneErbB ReceptorsHumansHydrogel, Polyethylene Glycol DimethacrylateLactic AcidNanoparticlesPeptidesPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerChitosanDexamethasoneErbB ReceptorsGE11 peptideHydrogel, Polyethylene Glycol DimethacrylateLactic AcidPeptidesPolyglycolic AcidPolylactic Acid-Polyglycolic Acid Copolymerchitosan thermosetting hydrogelEGFR targetingGE11 peptideintra-articular injectionPLGA-PEG nanoparticles

Identifiers

PMID30082640
PMCPMC6121689
OpenAlexW2887734524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.