Evidence map›Paper›PMID 30082489›Full record

ArticleThe oncologist2018

Pretreatment

Chengcheng Gong, Guang Ma, Xichun Hu, Yingjian Zhang, Zhonghua Wang, Jian Zhang, Yannan Zhao, Yi Li, Yizhao Xie, Zhongyi Yang and 1 more

3 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in The oncologist, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00601159 phase2completednot on this map

Phase Ⅱ Study of Gemcitabine and Cisplatin as First Line Combination Therapy in Patients With Triple-negative MBC

TypeinterventionalSponsorFudan UniversityRan2007 to 2010Enrolled70ConditionsMetastatic Breast CancerArmsgemcitabine and cisplatin
NCT01287624 phase3completednot on this map

A Phase III, Multicenter, Open-Label, Randomized Study of Gemcitabine Plus Cisplatin (GP) Versus Gemcitabine Plus Paclitaxel (GT) as First-Line Treatment in Patients With Advanced Triple-Negative Breast Cancer

TypeinterventionalSponsorFudan UniversityRan2011 to 2014Enrolled240ConditionsBreast CancerArmsGemcitabine,cisplatin, Gemcitabine, Paclitaxel
NCT02341911 phase2unknown statusnot on this map

A Phase II, Single-center, Open-Label, Randomized Study of Gemcitabine Plus Cisplatin (GP) Versus Gemcitabine Plus Carboplatin (GC) as First-Line Treatment in Patients With Advanced Triple-Negative Breast Cancer

TypeinterventionalSponsorFudan UniversityRan2015 to 2022Enrolled150ConditionsBreast CancerArmsGemcitabine,cisplatin, Gemcitabine,carboplatin
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. The impact of PET imaging on triple negative breast cancer: an updated evidence-based perspective.European journal of nuclear medicine and molecular imaging · 2024
    Pooled it
  2. Review
  3. Article
  4. Review
  5. PretreatmentCancer imaging : the official publication of the International Cancer Imaging Society · 2023
    Article
  6. Evaluation of tumour heterogeneity byBreast cancer research : BCR · 2022
    Article
  7. Article
  8. Heterogeneity derived fromCancer medicine · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. PretreatmentAnnals of nuclear medicine · 2021
    Article
  13. Article
  14. Article
  15. Heterogeneous parameters based onQuantitative imaging in medicine and surgery · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Chengcheng GongDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Guang MaDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Xichun HuDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Yingjian ZhangDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Zhonghua WangDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Jian ZhangDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Yannan ZhaoDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Yi LiDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Yizhao XieDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Zhongyi YangDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China yangzhongyi21@163.com pro_wangbiyun@163.com.
Biyun WangDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China yangzhongyi21@163.com pro_wangbiyun@163.com.
Fudan University Shanghai Cancer Center · CNShanghai Medical College of Fudan University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntratumoral heterogeneity of MATERIALS AND

methodsmTNBC patients from three clinical trials (NCT00601159, NCT01287624, and NCT02341911) with whole-body

resultsA total of 42 mTNBC patients were included in this study. The median PFS of patients with high HI-T (>1.9) and high MAX-T (>10.5) was significantly shorter than patients with low HI-T (<1.9;

conclusionHI and MAX measured among metastatic lesions on pretreatment IMPLICATIONS FOR PRACTICE: Intratumoral heterogeneity of

Indexed as

AdultFemaleFluorodeoxyglucose F18HumansMiddle AgedNeoplasm MetastasisSurvival AnalysisTreatment OutcomeTriple Negative Breast NeoplasmsFluorodeoxyglucose F1818F‐fluorodeoxyglucose positron emission tomography/computed tomographyGenetic heterogeneityMetastatic breast cancerPrognosisTriple‐negative breast neoplasms

Identifiers

PMID30082489
PMCPMC6263118
OpenAlexW2885938681

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.