Evidence map›Paper›PMID 30082421›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

SCN VIP Neurons Are Essential for Normal Light-Mediated Resetting of the Circadian System.

Jeff R Jones, Tatiana Simon, Lorenzo Lones, Erik D Herzog

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 153 citations in OpenAlex.

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  18. A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Jeff R JonesDepartment of Biology and.ORCID 0000-0002-8386-7798
Tatiana SimonDepartment of Biology and.
Lorenzo LonesNeuroscience Graduate Program, Washington University in St. Louis, St. Louis, Missouri 63130.
Erik D HerzogDepartment of Biology and herzog@wustl.edu.ORCID 0000-0001-7209-5174
Herzog College · ILWashington University in St. Louis · US

Funding

Multiscale Modeling of the Mammalian Circadian Clock: The Role of GABA SignalingU01EB021956 · NIBIB · UNIVERSITY OF MASSACHUSETTS AMHERST · PI HENSON, MICHAEL, HERZOG, ERIK · 2016 to 2019
$1.8M
MECHANISMS AND MODELING OF NETWORKED CIRCADIAN PACEMAKER SYNCHRONIZATIONR01GM096873 · NIGMS · WASHINGTON UNIVERSITY · PI DOYLE, FRANCIS J, HENSON, MICHAEL · 2011 to 2014
$1.1M
CRCNS: The balance between robustness and sensitivity in circadian synchronyR01NS095367 · NINDS · WASHINGTON UNIVERSITY · PI HERZOG, ERIK · 2015 to 2017
$566k
Hypocretinergic integration of circadian rhythms and sleepF32HL133772 · NHLBI · WASHINGTON UNIVERSITY · PI JONES, JEFFREY R · 2016 to 2018
$173k
NHLBI NIH HHS F32 HL133772NIBIB NIH HHS U01 EB021956NIGMS NIH HHS R01 GM096873NINDS NIH HHS R01 NS095367
6 · The paper itself

Abstract

The suprachiasmatic nucleus (SCN) synchronizes circadian rhythms in behavior and physiology to the external light cycle, but the mechanisms by which this occurs are unclear. As the neuropeptide vasoactive intestinal peptide (VIP) is important for circadian light responses, we tested the hypothesis that rhythmic VIP-producing SCN neurons mediate circadian light responses in male and female mice. Using

Indexed as

Action PotentialsAnimalsCalciumCircadian RhythmFemaleMaleMiceMotor ActivityPhotoperiodReceptors, Vasoactive Intestinal Peptide, Type IISuprachiasmatic NucleusSuprachiasmatic Nucleus NeuronsVasoactive Intestinal PeptideCalciumReceptors, Vasoactive Intestinal Peptide, Type IIVasoactive Intestinal Peptidecalciumcircadianlightneuropeptidesuprachiasmaticvasoactive intestinal peptide

Identifiers

PMID30082421
PMCPMC6596148
OpenAlexW2885548393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.