Evidence map›Paper›PMID 30082403›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion.

Ulrike Löber, Matthew Hobbs, Anisha Dayaram, Kyriakos Tsangaras, Kiersten Jones, David E Alquezar-Planas, Yasuko Ishida, Joanne Meers, Jens Mayer, Claudia Quedenau and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
11.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 64 citations in OpenAlex.

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  12. Geographic patterns of koala retrovirus genetic diversity, endogenization, and subtype distributions.Proceedings of the National Academy of Sciences of the United States of America · 2022
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  18. Molecular Diagnosis of Koala Retrovirus (KoRV) in South Australian Koalas (Animals : an open access journal from MDPI · 2021
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 5 countries.

Ulrike LöberDepartment of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, 10315 Berlin, Germany.
Matthew HobbsAustralian Museum Research Institute, Australian Museum, Sydney, NSW 2010, Australia.
Anisha DayaramDepartment of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, 10315 Berlin, Germany.
Kyriakos TsangarasDepartment of Translational Genetics, The Cyprus Institute of Neurology and Genetics, Nicosia 1683, Cyprus.
Kiersten JonesAustralian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, QLD 4067, Australia.
David E Alquezar-PlanasDepartment of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, 10315 Berlin, Germany.
Yasuko IshidaDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Joanne MeersAustralian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, QLD 4067, Australia.
Jens MayerDepartment of Human Genetics, Medical Faculty, University of Saarland, 66421 Homburg, Germany.
Claudia QuedenauMax Delbruck Center, The Berlin Institute for Medical Systems Biology, Genomics, 13125 Berlin, Germany.
Wei ChenMax Delbruck Center, The Berlin Institute for Medical Systems Biology, Genomics, 13125 Berlin, Germany.
Rebecca N JohnsonAustralian Museum Research Institute, Australian Museum, Sydney, NSW 2010, Australia.
Peter TimmsFaculty of Science, Health, Education & Engineering, University of the Sunshine Coast, Sippy Downs, QLD 4556, Australia.
Paul R YoungAustralian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, QLD 4067, Australia.
Alfred L RocaDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801; roca@illinois.edu greenwood@izw-berlin.de.
Alex D GreenwoodDepartment of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, 10315 Berlin, Germany; roca@illinois.edu greenwood@izw-berlin.de.
Leibniz Institute for Zoo and Wildlife Research · DEUniversity of Queensland · AUAustralian Museum · AUMax Delbrück Center · DEUniversity of Illinois Urbana-Champaign · USCyprus Institute of Neurology and Genetics · CYFreie Universität Berlin · DESaarland University · DEUniversity of the Sunshine Coast · AU

Funding

A singular opportunity to determine the evolutionary genetics of retroviral invasR01GM092706 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI ROCA, ALFRED LUIS · 2011 to 2013
$849k
NIGMS NIH HHS R01 GM092706
6 · The paper itself

Abstract

Endogenous retroviruses (ERVs) are proviral sequences that result from colonization of the host germ line by exogenous retroviruses. The majority of ERVs represent defective retroviral copies. However, for most ERVs, endogenization occurred millions of years ago, obscuring the stages by which ERVs become defective and the changes in both virus and host important to the process. The koala retrovirus, KoRV, only recently began invading the germ line of the koala (

Indexed as

Recombination, GeneticAnimalsEndogenous RetrovirusesFemaleMaleNew South WalesPhascolarctidaeendogenous retrovirusgenome evolutionkoala retrovirusrecombinationretrovirus

Identifiers

PMID30082403
PMCPMC6112702
OpenAlexW2886967317

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.