Evidence map›Paper›PMID 30082375›Full record

ArticleBiology open2018

Characterization of diabetic neuropathy progression in a mouse model of type 2 diabetes mellitus.

Cristian De Gregorio, David Contador, Mario Campero, Marcelo Ezquer, Fernando Ezquer

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 44 citations in OpenAlex.

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  14. Glial cell alterations in diabetes-induced neurodegeneration.Cellular and molecular life sciences : CMLS · 2024
    Review
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  16. Poly(l-lactic acid) Scaffold Releasing an αACS applied bio materials · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Cristian De GregorioCenter for Regenerative Medicine, Facultad de Medicina, Clínica Alemana- Universidad del Desarrollo, Santiago 7710162, Chile.
David ContadorCenter for Regenerative Medicine, Facultad de Medicina, Clínica Alemana- Universidad del Desarrollo, Santiago 7710162, Chile.
Mario CamperoDepartment of Neurology & Neurosurgery, Hospital José Joaquín Aguirre, Universidad de Chile, Santiago 7710162, Chile.
Marcelo EzquerCenter for Regenerative Medicine, Facultad de Medicina, Clínica Alemana- Universidad del Desarrollo, Santiago 7710162, Chile.
Fernando EzquerCenter for Regenerative Medicine, Facultad de Medicina, Clínica Alemana- Universidad del Desarrollo, Santiago 7710162, Chile eezquer@udd.cl.ORCID http://orcid.org/0000-0002-7696-4215
Universidad del Desarrollo · CLClínica Las Condes · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus (DM) is one of most common chronic diseases with an increasing incidence in most countries. Diabetic neuropathy (DN) is one of the earliest and main complications of diabetic patients, which is characterized by progressive, distal-to-proximal degeneration of peripheral nerves. The cellular and molecular mechanisms that trigger DN are highly complex, heterogeneous and not completely known. Animal models have constituted a valuable tool for understanding diabetes pathophysiology; however, the temporal course of DN progression in animal models of type 2 diabetes (T2DM) is not completely understood. In this work, we characterized the onset and progression of DN in BKS diabetic (

Indexed as

Animal modelAxonal degenerationDiabetic neuropathyPeripheral nervesType 2 diabetes mellitus

Identifiers

PMID30082375
PMCPMC6176942
OpenAlexW2887088891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.