Evidence map›Paper›PMID 30082328›Full record

ArticleG3 (Bethesda, Md.)2018

Null Mutation of the

Xiang Liu, Mengmeng Zhao, Yi Xie, Ping Li, Oumei Wang, Bingxin Zhou, Linlin Yang, Yao Nie, Lin Cheng, Xicheng Song and 2 more

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Genetic dissection of non-syndromic retinitis pigmentosa.Indian journal of ophthalmology · 2022
    Review
  10. Review
  11. Review
  12. Article
  13. Prognostic significance ofJournal of Cancer · 2021
    Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Xiang LiuKey Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical, University, 346 Guanhai Road, Yantai 264003, Shandong, P. R. China.
Mengmeng ZhaoKey Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical, University, 346 Guanhai Road, Yantai 264003, Shandong, P. R. China.
Yi XieKey Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical, University, 346 Guanhai Road, Yantai 264003, Shandong, P. R. China.
Ping LiKey Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical, University, 346 Guanhai Road, Yantai 264003, Shandong, P. R. China.
Oumei WangKey Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical, University, 346 Guanhai Road, Yantai 264003, Shandong, P. R. China.
Bingxin ZhouKey Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical, University, 346 Guanhai Road, Yantai 264003, Shandong, P. R. China.
Linlin YangKey Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical, University, 346 Guanhai Road, Yantai 264003, Shandong, P. R. China.
Yao NieKey Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical, University, 346 Guanhai Road, Yantai 264003, Shandong, P. R. China.
Lin ChengKey Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical, University, 346 Guanhai Road, Yantai 264003, Shandong, P. R. China.
Xicheng SongKey Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical, University, 346 Guanhai Road, Yantai 264003, Shandong, P. R. China.
Changzhu JinKey Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical, University, 346 Guanhai Road, Yantai 264003, Shandong, P. R. China hanfengchan@gmail.com Jincz63@hotmail.com.
Fengchan HanKey Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical, University, 346 Guanhai Road, Yantai 264003, Shandong, P. R. China hanfengchan@gmail.com Jincz63@hotmail.com.ORCID 0000-0002-0293-9965
Binzhou Medical University · CNBinzhou University · CNYuhuangding Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fascin2 (FSCN2) is an actin cross-linking protein that is mainly localized in retinas and in the stereocilia of hair cells. Earlier studies showed that a deletion mutation in human

Indexed as

HomozygoteMutationAnimalsBase SequenceBiopsyCarrier ProteinsCell CountDisease Models, AnimalDisease ProgressionElectroretinographyGene ExpressionGene FrequencyGene TargetingHair Cells, Auditory, OuterHearing LossHeterozygoteCarrier ProteinsfascinMicrofilament ProteinsTranscription Activator-Like Effector NucleasesFascin2hair cellhearing lossmutationretinitis pigmentosaTALEN

Identifiers

PMID30082328
PMCPMC6169377
OpenAlexW2889606535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.