Evidence map›Paper›PMID 30082321›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Identification and Analysis of Islet Antigen-Specific CD8

Hideki Ogura, Paula Preston-Hurlburt, Ana Luisa Perdigoto, Matthew Amodio, Smita Krishnaswamy, Pamela Clark, Hua Yu, Dieter Egli, Alexandra Fouts, Andrea K Steck and 1 more

Abstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Review
  3. The immunology of type 1 diabetes.Nature reviews. Immunology · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. T cell receptor sequencing in autoimmunity.Journal of life sciences (Westlake Village, Calif.) · 2020
    Article
  12. Article
  13. Enforcing the checkpoints: harnessing T-cell exhaustion for therapy of T1D.Current opinion in endocrinology, diabetes, and obesity · 2019
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hideki OguraDepartment of Immunobiology, Yale University, New Haven, CT 06520.ORCID 0000-0002-2116-0340
Paula Preston-HurlburtDepartment of Immunobiology, Yale University, New Haven, CT 06520.
Ana Luisa PerdigotoDepartment of Internal Medicine, Yale University, New Haven, CT 06520.ORCID 0000-0002-0348-9329
Matthew AmodioDepartment of Genetics and of Computer Science, Yale University, New Haven, CT 06520.ORCID 0000-0001-9478-0957
Smita KrishnaswamyDepartment of Genetics and of Computer Science, Yale University, New Haven, CT 06520.ORCID 0000-0001-5823-1985
Pamela ClarkDepartment of Immunobiology, Yale University, New Haven, CT 06520.
Hua YuDepartment of Immunobiology, Yale University, New Haven, CT 06520.ORCID 0000-0002-1691-2763
Dieter EgliNaomi Berrie Diabetes Center, Division of Molecular Genetics, Columbia University, New York, NY 10032.
Alexandra FoutsBarbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, CO 80045.
Andrea K SteckBarbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, CO 80045.
Kevan C HeroldDepartment of Immunobiology, Yale University, New Haven, CT 06520; kevan.herold@yale.edu.

Funding

Phase II Trial of HOKT3gamma 1 (ALA-ALA) in Type 1 DiabetesR01DK057846 · NIDDK · YALE UNIVERSITY · PI Kevan C Herold · 2000 to 2026
$11.1M
DIABETES MELLITUS &DISORDERS OF METABOLISMT32DK007058 · NIDDK · YALE UNIVERSITY · PI SONIA CAPRIO, Kevan C Herold · 1986 to 2026
$9.6M
Career Development Programs in Diabetes Research for Pediatrics EndocrinologistsK12DK094714 · NIDDK · YALE UNIVERSITY · PI TAMBORLANE, WILLIAM V · 2011 to 2020
$4.3M
Epigenetic, Protein, and Cellular Biomarkers of Beta Cell Function in T1DUC4DK104205 · NIDDK · YALE UNIVERSITY · PI HEROLD, KEVAN C · 2014 to 2014
$2.5M
NIDDK NIH HHS K12 DK094714NIDDK NIH HHS R01 DK057846NIDDK NIH HHS T32 DK007058NIDDK NIH HHS UC4 DK104205
6 · The paper itself

Abstract

Type 1 diabetes (T1D) is most likely caused by killing of β cells by autoreactive CD8

Indexed as

CD8-Positive T-LymphocytesDiabetes Mellitus, Type 1FemaleHumansInsulin-Secreting CellsMaleReceptors, Antigen, T-CellReceptors, Antigen, T-Cell

Identifiers

PMID30082321
PMCPMC6449153

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.