Evidence map›Paper›PMID 30082316›Full record

ArticleThe Journal of biological chemistry2018

The contribution of cross-talk between the cell-surface proteins CD36 and CD47-TSP-1 in osteoclast formation and function.

Srinivas V Koduru, Ben-Hua Sun, Joanne M Walker, Meiling Zhu, Christine Simpson, Madhav Dhodapkar, Karl L Insogna

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 41 citations in OpenAlex.

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  17. The Physiological and Pathological Role of Acyl-CoA Oxidation.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Srinivas V KoduruFrom the Departments of Medicine (Hematology) and Immunobiology and.ORCID 0000-0001-6827-2908
Ben-Hua SunDepartment of Medicine (Endocrinology), Yale School of Medicine, New Haven, Connecticut 06520.
Joanne M WalkerDepartment of Medicine (Endocrinology), Yale School of Medicine, New Haven, Connecticut 06520.
Meiling ZhuDepartment of Medicine (Endocrinology), Yale School of Medicine, New Haven, Connecticut 06520.
Christine SimpsonDepartment of Medicine (Endocrinology), Yale School of Medicine, New Haven, Connecticut 06520.
Madhav DhodapkarFrom the Departments of Medicine (Hematology) and Immunobiology and.
Karl L InsognaDepartment of Medicine (Endocrinology), Yale School of Medicine, New Haven, Connecticut 06520 karl.insogna@yale.edu.
Yale University · US

Funding

Targeting Thrombospondin 1 in Bone ResorptionR01AR060322 · NIAMS · YALE UNIVERSITY · PI DHODAPKAR, MADHAV V, INSOGNA, KARL LEONARD · 2011 to 2015
$1.8M
NIAMS NIH HHS R01 AR060322
6 · The paper itself

Abstract

Antibody-mediated blockade of cluster of differentiation 47 (CD47)-thrombospondin-1 (TSP-1) interactions blocks osteoclast formation

Indexed as

AnimalsBone ResorptionCD36 AntigensCD47 AntigenFemaleHypercalcemiaMembrane ProteinsMiceMice, KnockoutNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide SynthaseOsteoclastsOsteogenesisParathyroid HormoneSignal Detection, PsychologicalCD36 AntigensCD47 AntigenMembrane ProteinsNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide SynthaseParathyroid HormoneThrombospondin 1bonebone resorptionCD36CD47osteoblastosteoclastosteocyteosteoporosisparathyroid hormonethrombospondinTSP-1

Identifiers

PMID30082316
PMCPMC6166722
OpenAlexW2887437160

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.