Evidence map›Paper›PMID 30082295›Full record

ArticleAntimicrobial agents and chemotherapy2018

Local Skin Inflammation in Cutaneous Leishmaniasis as a Source of Variable Pharmacokinetics and Therapeutic Efficacy of Liposomal Amphotericin B.

Gert-Jan Wijnant, Katrien Van Bocxlaer, Amanda Fortes Francisco, Vanessa Yardley, Andy Harris, Mo Alavijeh, Sudaxshina Murdan, Simon L Croft

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. iScience · 2023
    Article
  5. Case Report: Extensive Facial Cutaneous Leishmaniasis in a Neonate.The American journal of tropical medicine and hygiene · 2023
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. In-situ immune profile of polymorphic vs. macular Indian Post Kala-azar dermal leishmaniasis.International journal for parasitology. Drugs and drug resistance · 2019
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Pharmacokinetics of neutron-irradiated meglumine antimoniate inThe journal of venomous animals and toxins including tropical diseases · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Gert-Jan WijnantDepartment of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Katrien Van BocxlaerDepartment of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Amanda Fortes FranciscoDepartment of Pathogen Molecular Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Vanessa YardleyDepartment of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Andy HarrisPharmidex Pharmaceutical Services Ltd., London, United Kingdom.
Mo AlavijehPharmidex Pharmaceutical Services Ltd., London, United Kingdom.
Sudaxshina MurdanDepartment of Pharmaceutics, UCL School of Pharmacy, London, United Kingdom.
Simon L CroftDepartment of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom simon.croft@lshtm.ac.uk.
London School of Hygiene & Tropical Medicine · GBPharmidex (United Kingdom) · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disfiguring skin lesions caused by several species of the

Indexed as

Amphotericin BAnimalsAntiprotozoal AgentsDisease Models, AnimalFemaleInflammationLeishmaniasis, CutaneousMiceMice, Inbred BALB CAmphotericin BAntiprotozoal Agentsliposomal amphotericin Bcutaneous leishmaniasisinflammationliposomal amphotericin Bpharmacokinetics

Identifiers

PMID30082295
PMCPMC6153808
OpenAlexW2887054155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.