Evidence map›Paper›PMID 30082289›Full record

ArticleAntimicrobial agents and chemotherapy2018

Studies on Aminoglycoside Susceptibility Identify a Novel Function of KsgA To Secure Translational Fidelity during Antibiotic Stress.

Jin Zou, Wenwen Zhang, Hongjie Zhang, Xiaohua Douglas Zhang, Bo Peng, Jun Zheng

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Compendium of RNA modifications for bacterial stress adaptation.Microbiology and molecular biology reviews : MMBR · 2026
    Review
  2. Article
  3. Mechanistic insights into 50Science advances · 2025
    Article
  4. Article
  5. Article
  6. Antibiotics (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Real-time measurements of aminoglycoside effects on protein synthesis in live cells.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. Non-walled sphericalEmerging microbes & infections · 2020
    Article
  13. Article
  14. Structural and catalytic roles of the human 18The Journal of biological chemistry · 2020
    Article
  15. Article
  16. Antibiotic Resistance Patterns ofFrontiers in microbiology · 2020
    Article
  17. Alarmone Ap4A is elevated by aminoglycoside antibiotics and enhances their bactericidal activity.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jin ZouFaculty of Health Sciences, University of Macau, Macau SAR, China.
Wenwen ZhangFaculty of Health Sciences, University of Macau, Macau SAR, China.
Hongjie ZhangFaculty of Health Sciences, University of Macau, Macau SAR, China.
Xiaohua Douglas ZhangFaculty of Health Sciences, University of Macau, Macau SAR, China.
Bo PengSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0002-5698-6097
Jun ZhengFaculty of Health Sciences, University of Macau, Macau SAR, China JunZheng@umac.mo.ORCID 0000-0001-6329-4518
University of Macau · MOSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic resistance has become a global crisis. Studies on the mechanism of bacterial tolerance to antibiotics will not only increase our conceptual understanding of bacterial death but also provide potential targets for novel inhibitors. We screened a mutant library containing a full set of in-frame deletion mutants of

Indexed as

Acinetobacter baumanniiAminoglycosidesAnti-Bacterial AgentsEscherichia coli K12KanamycinRNA, Ribosomal, 16SVirulenceAminoglycosidesAnti-Bacterial AgentsKanamycinkasugamycinRNA, Ribosomal, 16SAcinetobacter baumanniiaminoglycosidesKsgAtranslational fidelityvirulence

Identifiers

PMID30082289
PMCPMC6153849
OpenAlexW2887196153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.