Evidence map›Paper›PMID 30081938›Full record

ArticleParasites & vectors2018

The genetic diversity of Borrelia afzelii is not maintained by the diversity of the rodent hosts.

Claudia E Coipan, Gilian L A van Duijvendijk, Tim R Hofmeester, Katsuhisa Takumi, Hein Sprong

Abstract read
In one paragraph

Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Molecular Identification ofInternational journal of molecular sciences · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Circulation ofPathogens (Basel, Switzerland) · 2021
    Article
  10. Article
  11. Evolutionary Genetics ofCurrent issues in molecular biology · 2021
    Review
  12. Human and Veterinary Vaccines for Lyme Disease.Current issues in molecular biology · 2021
    Article
  13. Article
  14. Evolutionary ecology of Lyme Borrelia.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020
    Review
  15. Multiple Tick-Borne Pathogens inPathogens (Basel, Switzerland) · 2020
    Article
  16. Tripartite Interactions amongPathogens (Basel, Switzerland) · 2020
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Claudia E CoipanLaboratory of Entomology, Wageningen University, Wageningen, The Netherlands. Claudia.Coipan@rivm.nl.ORCID http://orcid.org/0000-0003-1655-5177
Gilian L A van DuijvendijkLaboratory of Entomology, Wageningen University, Wageningen, The Netherlands.
Tim R HofmeesterResource Ecology Group, Wageningen University, Wageningen, The Netherlands.
Katsuhisa TakumiLaboratory for Zoonoses and Environmental Microbiology, National Institute for Public Health and Environment (RIVM), Bilthoven, The Netherlands.
Hein SprongLaboratory of Entomology, Wageningen University, Wageningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSmall mammals are essential in the enzootic cycle of many tick-borne pathogens (TBP). To understand their contribution to the genetic diversity of Borrelia afzelii, the most prevalent TBP in questing Ixodes ricinus, we compared the genetic variants of B. afzelii at three distinct genetic loci. We chose two plasmid loci, dbpA and ospC, and a chromosomal one, IGS.

resultsWhile the larvae that fed on shrews (Sorex sp.) tested negative for B. afzelii, those fed on bank voles (Myodes glareolus) and wood mice (Apodemus sylvaticus) showed high infection prevalences of 0.13 and 0.27, respectively. Despite the high genetic diversity within B. afzelii, there was no difference between wood mice and bank voles in the number and types of B. afzelii haplotypes they transmit.

conclusionsThe genetic diversity in B. afzelii cannot be explained by separate enzootic cycles in wood mice and bank voles.

Indexed as

Genetic VariationAnimalsArvicolinaeBorrelia burgdorferi GroupHaplotypesHost SpecificityIxodesMurinaePlasmidsBorrelia burgdorferi (s.l.)dbpAIGSIxodes ricinus larvaeospCRodents

Identifiers

PMID30081938
PMCPMC6090804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.