ArticleBMC complementary and alternative medicine2018
Investigation of biological activities of the flowers of Lagerstroemia speciosa, the Jarul flower of Bangladesh.
Article in BMC complementary and alternative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 35 citations in OpenAlex.
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- Chromosome-level genome assembly of banaba (Lagerstroemia speciosa L.).Scientific data · 2024Article
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- Applying Network Pharmacology and Molecular Docking in the Screening for Molecular Mechanisms of Ampalaya (Acta medica Philippina · 2024Article
- Antimicrobial activities of Asian plant extracts against pathogenic and spoilage bacteria.Food science and biotechnology · 2023Article
- Antibacterial, Antioxidant, Larvicidal and Anticancer Activities of Silver Nanoparticles Synthesized Using Extracts from Fruits ofMolecules (Basel, Switzerland) · 2022Article
- Identification, ADMET evaluation and molecular docking analysis of Phytosterols from Banaba (In silico pharmacology · 2021Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLagerstroemia speciosa (L.) Pers. (Family: Lythraceae) is used in traditional medicine in the treatment of diarrhea, diabetes and other diseases. The study was performed to conduct antioxidant, cytotoxic, thrombolytic, membrane stabilizing, antimicrobial, peripheral and central analgesic and hypoglycemic activity assays and phenobarbitone sodium-induced sleeping time test using crude methanol extract of flowers of L. speciosa and its different partitionates.
methodThe antioxidant potential was evaluated by determining the ability of the samples to scavenge 1, 1-diphenyl-2-picrylhydrazyl (DPPH) free radical. The cytotoxic potential was examined following the procedures of brine shrimp lethality bioassay. Thrombolytic potential was assayed using streptokinase as standard. The samples were subjected to membrane stabilizing activity assay under heat induced condition. Antimicrobial potential was observed by disc diffusion method. The ability of the extract to inhibit writhing induced by acetic acid was determined in peripheral analgesic activity assay. The extract was also tested for central analgesic and hypoglycemic activities by tail flicking and tail tipping methods in Swiss albino mice model, respectively. CNS depressant activity was evaluated by an assay in which sleep was induced in mice using phenobarbitone sodium.
resultsThe chloroform soluble fraction of L. speciosa extract demonstrated the highest antioxidant activity (IC
conclusionsFrom our investigation, it can be suggested that, the extract should be further studied for possible phytochemicals responsible for the observed biological activities.
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