Evidence map›Paper›PMID 30081863›Full record

Trial reportBMC psychiatry2018

Effect of virtual reality aggression prevention training for forensic psychiatric patients (VRAPT): study protocol of a multi-center RCT.

Stéphanie Klein Tuente, Stefan Bogaerts, Sarah van IJzendoorn, Wim Veling

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07434479 (A Virtual Reality Mindfulness Application for Aggression in Schizophrenia), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07434479 narecruitingnot on this mapstarted 2026, after this paper: background citation

A Virtual Reality Mindfulness Application for Aggression in Schizophrenia

TypeinterventionalSponsorManhattan Psychiatric CenterRan2026 to 2027Enrolled58ConditionsSchizophrenia Disorder, Schizoaffecitve Disorder, AggressionArmsMindfulness-Based Virtual Reality Intervention
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Risk assessment for aggressive behaviour in schizophrenia.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Psychological interventions for antisocial personality disorder.The Cochrane database of systematic reviews · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stéphanie Klein TuenteDepartment of Psychoses, University Medical Center Groningen, Hanzeplein 1, 9713, GZ, Groningen, The Netherlands. s.klein.tuente@umcg.nl.ORCID 0000-0002-4964-593X
Stefan BogaertsDepartment of Developmental Psychology, Tilburg University, Prof Cobbenhagenlaan 225, PO Box 90153, 5000, LE, Tilburg, The Netherlands.
Sarah van IJzendoornFivoor, Fivoor Science & Treatment Innovation, Kijvelandsekade 1, 3172, AB, Poortugaal, The Netherlands.
Wim VelingDepartment of Psychoses, University Medical Center Groningen, Hanzeplein 1, 9713, GZ, Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany patients residing in forensic psychiatric centers have difficulties regulating their aggression in an adequate manner. Therefore, they are frequently involved in conflicts. Evidenced-based aggression therapies in forensic psychiatry are scarce, and due to the highly secured environment, it is hard to practice real-life provocations. We have developed a Virtual Reality aggression prevention training (VRAPT), providing safe virtual environments, in which patients can practice controlling their aggressive behaviors in an adequate way. The main objective of this study is to examine whether VRAPT is effective in reducing aggression among forensic psychiatric inpatients.

methodsFour forensic psychiatric centers in the Netherlands are participating in this study. Participants will be randomly assigned to either VRAPT or a waiting list. The two groups will be compared at several different time points: baseline (12 weeks before intervention), pre-intervention, post-intervention and at 12 weeks follow-up. After follow-up measurements are completed, participants from the waiting list will also receive VRAPT. The primary outcome is level of aggressive behavior, consisting of staff-reported and self-reported measures. Secondary outcomes are self-report questionnaires on e.g., anger, impulsivity and aggression. DISCUSSION: To the best of our knowledge this is the first study to examine the effectiveness of a VR aggression prevention training in forensic psychiatric centers. Further details on the methodological issues are discussed in this paper.

trial registrationDutch Trial Register ( NTR, TC = 6340 ). Retrospectively registered 14-04-2017.

Indexed as

AdultAggressionAngerFemaleFollow-Up StudiesForensic PsychiatryHumansInpatientsMaleMental DisordersNetherlandsRetrospective StudiesSelf ReportSingle-Blind MethodSurveys and QuestionnairesTreatment OutcomeAggressionAggressive behaviorForensic psychiatrySIP modelVirtual reality

Identifiers

PMID30081863
PMCPMC6091200

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.