ArticleBMC cancer2018
Favorable mortality-to-incidence ratios of kidney Cancer are associated with advanced health care systems.
Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Hyaluronan accumulation is associated with reduced hyaluronidase expression in renal cell carcinoma, with CD44, HAS1, and HYAL2 emerging as prognostic markers.The journal of pathology. Clinical research · 2025Article
- A comparative analysis of global and Chinese trends in the burden of kidney cancer from 1990 to 2021.Scientific reports · 2025Article
- Analyzing the cancer mortality-to-incidence ratios and health expenditures in the aging population: a 20-year comparative study across high-income countries.Frontiers in aging · 2025Article
- Histopathologic classification and immunohistochemical features of papillary renal neoplasm with potential therapeutic targets.Journal of pathology and translational medicine · 2024Article
- Article
- Targeting the Adenosine A2A Receptor as a Novel Therapeutic Approach for Renal Cell Carcinoma: Mechanisms and Clinical Trial Review.Pharmaceutics · 2024Review
- Article
- Gender differences in leukemia outcomes based on health care expenditures using estimates from the GLOBOCAN 2020.Archives of public health = Archives belges de sante publique · 2023Article
- Favorable Mortality-to-Incidence Ratio Trends of Lung Cancer in Countries with High Computed Tomography Density.Medicina (Kaunas, Lithuania) · 2023Article
- Improved Trends in the Mortality-to-Incidence Ratios for Liver Cancer in Countries with High Development Index and Health Expenditures.Healthcare (Basel, Switzerland) · 2023Article
- Patterns of better breast cancer care in countries with higher human development index and healthcare expenditure: Insights from GLOBOCAN 2020.Frontiers in public health · 2023Article
- Mortality-to-Incidence Ratio for Nasopharyngeal Carcinoma Is Associated with Health Expenditure.Healthcare (Basel, Switzerland) · 2022Article
- Trends in Incidence and Mortality of Kidney Cancer in a Northern Italian Province: An Update to 2020.Biology · 2022Article
- Digestive cancer incidence and mortality among young adults worldwide in 2020: A population-based study.World journal of gastrointestinal oncology · 2022Article
- Favorable Lip and Oral Cancer Mortality-to-Incidence Ratios in Countries with High Human Development Index and Expenditures on Health.International journal of environmental research and public health · 2021Article
- Improved trends of lung cancer mortality-to-incidence ratios in countries with high healthcare expenditure.Thoracic cancer · 2021Article
- Trends of Testicular Cancer Mortality-to-Incidence Ratios in Relation to Health Expenditure: An Ecological Study of 54 Countries.International journal of environmental research and public health · 2021Article
- Trends in the kidney cancer mortality-to-incidence ratios according to health care expenditures of 56 countries.Scientific reports · 2021Article
- Improvement in the Mortality-to-Incidence Ratios for Gastric Cancer in Developed Countries With High Health Expenditures.Frontiers in public health · 2021Article
- Gender differences in trends of bladder cancer mortality-to-incidence ratios according to health expenditure in 55 countries.PloS one · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe advancements in cancer therapy have improved the clinical outcomes of cancer patients in recent decades. However, advanced cancer therapy is expensive and requires good health care systems. For kidney cancer, no studies have yet established an association between clinical outcome and health care disparities.
methodsWe used the mortality-to-incidence ratio (MIR) for kidney cancer as a marker of clinical outcome to compare World Health Organization (WHO) country rankings and total expenditures on health/gross domestic product (e/GDP) using linear regression analyses.
resultsWe included 57 countries based on data from the GLOBOCAN 2012 database. We found that more highly developed regions have higher crude and age-standardized rates of kidney cancer incidence and mortality, but a lower MIR, when compared to less developed regions. North America has the highest crude rates of incidence, but the lowest MIRs, whereas Africa has the highest MIRs. Furthermore, favorable MIRs are correlated with countries with good WHO rankings and high e/GDP expenditures (p < 0.001 and p = 0.013, respectively).
conclusionsKidney cancer MIRs are positively associated with the ranking of health care systems and health care expenditures.
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